Results 121 to 130 of about 175,387 (374)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

A hegységképződéstől a karsztokig. Beszélgetés Veress Mártonnal [Interjú] = From Mountain Formation to Karsts: Conversation with Márton Veress [Interview]

open access: yesModern Geográfia
Márton Veress was born on February 7, 1946 in Szombathely, Hungary. He graduated from the József Attila University as a teacher of Biology and Geography. He became the doctor of Hungarian Academy of Sciences in 2004.
Pusztai-Eredics, Alexandra   +1 more
doaj   +1 more source

Spartan Daily, May 25, 1937 [PDF]

open access: yes, 1937
Volume 25, Issue 142https://scholarworks.sjsu.edu/spartandaily/2626/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Awards as Signals [PDF]

open access: yes
Awards are widespread in all countries and are prevalent both in the public sphere and in the private sector. This paper argues, and empirically supports, that awards serve public functions and economists should take them seriously.
Bruno S. Frey, Susanne Neckermann
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Publication patterns of award-winning forest scientists and implications for the ERA journal ranking

open access: yes, 2011
Publication patterns of 79 forest scientists awarded major international forestry prizes during 1990-2010 were compared with the journal classification and ranking promoted as part of the 'Excellence in Research for Australia' (ERA) by the Australian ...
Vanclay, Jerome K
core   +1 more source

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