Results 41 to 50 of about 47,738 (213)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Vegetable oil characteristics enhance the phytotoxicity of pinoxaden and haloxyfop-R-methyl on littleseed canarygrass Phalaris minor Retz.

Journal of Crop Protection, 2020
It is possible to increase the efficacy of herbicides by adding vegetable oils to the spray tank. In order to evaluate and study this fact a greenhouse study was conducted.
Mehdi Rastgoo, Masoud Kargar, Hamze Assadollahi   +2 more
doaj  

Analysis of Forced Spatial Vibrations of a Centrifugal Pump Impeller with Axial Forces Balancing Device

International Journal of Applied Mechanics and Engineering, 2016
In this paper, a model of a pump impeller with annular seals and a balancing device, used as a combined support-seal assembly, is considered. The forced coupled radial, angular and axial vibrations of the rotor are determined with consideration of ...
A. Zhulyov, V. Martsinkovsky, C. Kundera
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Strain Behavior of Short Concrete Columns Reinforced with GFRP Spirals

Buildings
This paper presents a comprehensive study focused on evaluating the strain generated within short concrete columns reinforced with glass-fiber-reinforced polymer (GFRP) bars and spirals under concentric compressive axial loads.
Loai Alkhattabi, Ahmed H. Ali, Hamdy M. Mohamed, Ahmed Gouda   +3 more
doaj   +1 more source

TESTING THE INTERACTION OF HEART LEFT VENTRICLE AND CONTINUOUS-FLOW PUMP ON A MOCK CIRCULATION MODEL UNDER NORMAL AND PATHOLOGICAL CONDITIONS

Вестник трансплантологии и искусственных органов, 2015
Introduction. The preliminary study of new developed pumps for circulatory support on the hydrodynamic circulation model is an important step in the process of their designing.
G. P. Itkin, A. A. Drobyshev, O. Yu. Dmitrieva, A. S. Buchnev, A. A. Sysoev   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Research on Axle Box Steel Spring Fractures for a Certain Type of Rail Vehicle

Chengshi guidao jiaotong yanjiu
ObjectiveIn response to the mass fracture problems of rail vehicle axle box steel springs in a certain region of China during application, it is necessary to analyze the spring fracture causes and develop relevant measures to address this issue. Method A
Yunpeng WANG, Xiaofeng LI, Xianpeng NIE, Qingwei SONG   +3 more
doaj   +1 more source