Results 91 to 100 of about 5,747,014 (299)
Streamline curvature computational programme for axial compressor performance prediction [PDF]
, 1987 Accurate prediction of overall performance is vital if the extremely high design and development costs of modern high speed compressors are to be minimised.
Barbosa, J. R.
core +2 more sources
Oftalʹmologiâ, 2018 Objective: to determine optimal method of progressive myopia optical correction in children and adolescents.Patients and methods. Conducted 5-year prospective clinical and instrumental examination of 494 children with myopia using orthokeratology lenses,
M. M. Sitka +2 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Cahiers d'Études du Religieux- Recherches Interdisciplinaires, 2022 Jérôme Lagouanère
doaj +1 more source
Search for a Common Ground: Jaspers on Human Existence, Cosmopolitanism and Philosophical Faith
CauriensiaIn the wake of Kant’s Copernican Turn, Karl Jaspers underscores the inherent limits of human cognition and action. To navigate these limitations, he advocates for intercultural communication at a global level.
Mario Wenning
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Finite element prediction of the ultimate axial load capacity of V-section band clamps [PDF]
, 2009 Band clamps with a flat bottomed V-section are used to connect a pair of circular flanges to provide a joint with significant axial strength. Despite the wide application of Vband clamps, their behaviour is not fully understood and the ultimate axial ...
Barrans, Simon +3 more
core +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source