Results 61 to 70 of about 88,526 (267)

Elastic Behavior and Load-Carrying Capacity of Longitudinal Shuttle-Shaped Concrete-Filled Steel Column with Cruciform Sections

open access: yesBuildings
Longitudinal shuttle-shaped concrete-filled steel column with cruciform sections (LSS-CFST-CS) is highly valued by architects and structural engineers for its distinctive appearance and significant architectural impact in spatial steel structures ...
Boli Zhu   +3 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Performance-Based Multi-Objective Optimization of Four-Limb CFST Lattice Columns

open access: yesBuildings
In this paper, the low-cycle reciprocating load test was carried out on four-limb concrete-filled steel tubular (CFST) lattice columns with different slenderness ratios and axial compression ratios, and the seismic performance was studied.
Junjie He   +6 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Experimental Study on and Finite Element Analysis of the Axial Compression Bearing Capacity of a UHPC Transfer Device for Pre-Stressed Anti-Floating Anchor Rods

open access: yesBuildings
A new UHPC pre-stress transfer device is proposed for pre-stressed anti-floating anchor rods. To investigate the axial compression performance of the device during pre-stressing, physical experiments and a finite element verification were conducted on ...
Yi Zhu   +4 more
doaj   +1 more source

Electromagnetic Force Distribution and Axial Deformation Uniformity Analysis of Dual-Coil Electromagnetic Tube Compression Method

open access: yesIEEE Access, 2020
In the conventional electromagnetic tube expansion, axial distribution of the electromagnetic force is not uniform along the workpiece. This results in uneven axial deformation of the deformed tube and restricts the full industrial implementation of this
Li Qiu   +5 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Local stability analysis of axial compression members with welded box-shaped section of Q690 high strength steel

open access: yes上海师范大学学报. 自然科学版
High strength steel welded box-shaped axial compression members have been widely used in steel structure engineering. In this paper, ANSYS analysis software was adopted to establish a finite element model considering the local geometrical initial defect ...
ZHAO Chuandou, YANG Yonghua
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

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