Results 61 to 70 of about 906,003 (303)

Bearing capacity of UHPC-filled circular steel tube short column under axial compression

open access: yesGrađevinar
This study establishes a predictive formula for the axial compression bearing capacity of Ultra High Performance Concrete (UHPC) filled circular steel tube (circular UHPCFST) short columns. The basis for establishing this formula is the derivation method
Shengbing Fang
doaj   +1 more source

Stochastic axial compressor variable geometry schedule optimisation [PDF]

open access: yes, 2011
The design of axial compressors is dictated by the maximisation of flow efficiency at on design conditions whereas at part speed the requirement for operation stability prevails.
Singh, R.   +7 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Study on Strain Resistance Effect of Smart Concrete Under Triaxial Compression

open access: yes工程科学与技术, 2013
:The strain resistance effect of smart concrete under triaxial compression was studied,and compared with the result measured under uniaxial compression.The results showed that during elastic stage of deformation,the axial resistance decreases with the ...
郑立霞   +3 more
doaj  

Effect of the axial load on the dynamic response of the wrapped CFRP reinforced concrete column under the asymmetrical lateral impact load.

open access: yesPLoS ONE, 2023
This study investigated the impact of axial load on the dynamic response of reinforced concrete (RC) members to asymmetrical lateral impact loads. A series of asymmetrical-span impact tests were conducted on circular and square RC members with and ...
Khalil Al-Bukhaiti   +7 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Study on Creep Compression Characteristics of Pressure-Bearing Graded Crushed Rock

open access: yesBuildings
To study the creep compression characteristics and evolution mechanism of pressure-bearing graded crushed rock under constant load. Creep compression tests of crushed rock were conducted using the self-developed confined compression test system under ...
Yu Tian   +4 more
doaj   +1 more source

Femoral periprosthetic fracture treatment using the Ortho-Bridge System: a biomechanical study

open access: yesJournal of Orthopaedic Surgery and Research, 2022
Background We undertook a comparative biomechanical study of type B1 fractures around femoral prostheses following cemented hip arthroplasty using the Ortho-Bridge System (OBS) and a locking compression plate/locking attachment plate structure (LCP + LAP)
Yuntao Long   +5 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

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