Results 61 to 70 of about 278,730 (305)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Femoral periprosthetic fracture treatment using the Ortho-Bridge System: a biomechanical study

Journal of Orthopaedic Surgery and Research, 2022
Background We undertook a comparative biomechanical study of type B1 fractures around femoral prostheses following cemented hip arthroplasty using the Ortho-Bridge System (OBS) and a locking compression plate/locking attachment plate structure (LCP + LAP)
Yuntao Long, Yubin Qi, Guilai Zuo, Qingjie Zhang, Zhenlin Liu, Wen Wang   +5 more
doaj   +1 more source

A recursive-faulting model of distributed damage in confined brittle materials [PDF]

, 2006
We develop a model of distributed damage in brittle materials deforming in triaxial compression based on the explicit construction of special microstructures obtained by recursive faulting.
Conti, S., Ortiz, M., Pandolfi, A.
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Study on Creep Compression Characteristics of Pressure-Bearing Graded Crushed Rock

Buildings
To study the creep compression characteristics and evolution mechanism of pressure-bearing graded crushed rock under constant load. Creep compression tests of crushed rock were conducted using the self-developed confined compression test system under ...
Yu Tian, Mei Zhi, Jie Zhou, Pengfei Ji, Shitong Peng   +4 more
doaj   +1 more source

Axial Compression Behavior of Recycled Concrete Filled Steel Tubular Short Columns after High Temperature

Advances in Civil Engineering, 2022
This article is devoted to study the axial compression behaviour of recycled concrete-filled steel tubular (RCFST) columns after high temperature. Several axial compression members’ internal mechanisms are analyzed by combining experimental and finite ...
Xiao Liu, Siying Liu, Yanchuan Hui, Xuexin Zhang, Bing Wang, Lei Zhao   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Behavior of Magnetically-Driven Concrete (MDC) Filled Double-Skin GFRP Tubes (CFDGT) Under Axial Compression

Frontiers in Built Environment, 2022
In order to study the axial compression behavior of magnetically-driven concrete (MDC) filled double-skin GFRP tubes (CFDGT), the axial compression test was conducted on eight columns (the length of columns ranged from 1,000 mm to 3,000 mm). For the MDC,
Xian-Song Xie, Ju Chen, Jun Wang, Cheng-Bin Liu   +3 more
doaj   +1 more source

Collective excitations of a degenerate gas at the BEC-BCS crossover

, 2004
We study collective excitation modes of a fermionic gas of $^6$Li atoms in the BEC-BCS crossover regime. While measurements of the axial compression mode in the cigar-shaped trap close to a Feshbach resonance confirm theoretical expectations, the radial ...
A. Altmeyer, A. J. Leggett, C. Chin, J. Hecker Denschlag, L. Pitaevski, M. Bartenstein, P. Nozières, R. Grimm, S. Jochim, S. Riedl   +9 more
core   +1 more source

Metallic tube type energy absorbers: a synopsis [PDF]

, 2007
This paper presents an overview of energy absorbers in the form of tubes in which the material used is predominantly mild steel and/or aluminium. A brief summary is also made of frusta type energy absorbers.
A.G. Olabi, Avalle, Calladine, Colokoglu, DeRuntz, Edmund Morris, Ezra, Ghosh, Guillow, Gupta, Gupta, Gupta, Harrigan, Hsu, Huang, Huang, Hui, Jiang, Jing, Johnson, Johnson, Johnson, Johnson, Jones, Kardaras, Kinkead, Langseth, Leu, Liu, Lu, Lu, Lu, M.S.J. Hashmi, Miscow, Morris, Morris, Morris, Nagel, Nagel, Nagel, Reddy, Reddy, Reddy, Reddy, Reddy, Redwood, Reid, Reid, Reid, Reid, Reid, Reid, Reid, Reid, Rossi, Sherbourne, Shim, Shrive, Silva-Gomes, Sowerby, Stronge, Su, Su, Tam, Thomas, Thomas, Thomas, Uddin, Wang, Wasiowych, Webb, Whitworth, Wierzbicki, Wu, Wu, Wu, Zeinoddini, Zhang, Zhao, Zhao, Zukas   +80 more
core   +1 more source