Results 61 to 70 of about 379,899 (332)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The Design of a semi-prefabricated LVL-concrete composite floor [PDF]

, 2012
This paper describes the design of a novel semi-prefabricated LVL-concrete composite floor that has been developed in New Zealand. In this solution, the floor units made from LVL joists and plywood are prefabricated in the factory and transported to the ...
Fragiacomo, Massimo, Yeoh, David
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Axial Compression Prediction and GUI Design for CCFST Column Using Machine Learning and Shapley Additive Explanation

Buildings, 2022
Axial bearing capacity is the key index of circular concrete-filled steel tubes (CCFST). A hybrid PSO-ANN model consisting of an artificial neural network (ANN) optimized with particle swarm algorithm (PSO) was proposed to reliably and accurately predict
Xuerui Liu, Yanqi Wu, Yisong Zhou
doaj   +1 more source

New Pressure-Induced Polymorphic Transitions of Anhydrous Magnesium Sulfate

, 2017
The effects of pressure on the crystal structure of the three known polymorphs of magnesium sulfate have been theoretically study by means of DFT calculations up to 45 GPa.
Benmakhlouf, A., Bentabet, A., Bouchenafa, M., Bouhemadou, A., Errandonea, D., Maabed, S.   +5 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Axial Compressive Performance of Steel-Reinforced UHPC-Filled Square Stainless-Steel Tube

Buildings, 2022
To study the axial compression performance of a steel-reinforced ultra-high-performance concrete-filled square stainless-steel tube (SR-UHPCFSSST), eight specimens were designed with different length-to-diameter ratios and skeleton contents, and axial ...
Zhan Cheng, Junhua Li, Chuangchuang Wu, Tianyi Zhang, Guofeng Du   +4 more
doaj   +1 more source

Mechanical Design of Superconducting Accelerator Magnets

, 2015
This paper is about the mechanical design of superconducting accelerator magnets. First, we give a brief review of the basic concepts and terms. In the following sections, we describe the particularities of the mechanical design of different types of ...
Toral, Fernando
core   +1 more source

Axial Compression Performance and Ultrasonic Testing of Multicavity Concrete-Filled Steel Tube Shear Wall under Axial Load

, 2020
In this study, the mechanical performance of multicavity concrete-filled steel tube (CFST) shear wall under axial compressive loading is investigated through experimental, numerical, and theoretical methodologies.
Hongbo Li, Pengfei Yan, Hao Sun, Jianguang Yin   +3 more
semanticscholar   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source