Results 51 to 60 of about 30,823 (299)

Experimental Performance Study on Axial Compressive Load-Bearing Capacity of Steel Slag Micropowder Ecotype UHPC of Short Columns Steel Pipe

open access: yesApplied Sciences
In order to study the axial compression performance of steel pipe concrete short columns filled with steel slag micronized ultra-high-performance concrete (UHPC), this paper designs 27 steel pipe UHPC short columns for axial compression test and compares
Shangqi Guo   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Axial Compressive Performance of Steel-Reinforced Concrete Columns with Monosymmetric Cross-Shaped Steel

open access: yesAdvances in Civil Engineering, 2021
The axial compressive performance of steel-reinforced concrete columns with monosymmetric cross-shaped steel (SRCC-MCS) was investigated in this study.
Jipeng Yu   +3 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Virtual testing of post-buckling behaviour of metallic stiffened panel [PDF]

open access: yes, 2011
The aim of the project presented in this thesis is to demonstrate a modelling method for predicting the variability in the ultimate load of stiffened panel under axial compression due to manufacturing variability.
Wang, Yang
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Preliminary aerothermal design of axial compressors [PDF]

open access: yes, 2013
This dissertation documents a compressor preliminary design study conducted by the author in fulfilment of his MSc thesis requirements. The compressor is intended for a new development engine within the 20Klbf thrust category, planned to be used on a ...
Piscopo, Giovanni
core  

Seismic Performance of Precast Short-Limb Shear Wall with the Bundled Connection at Different Axial Compression Ratios

open access: yes, 2023
In order to investigate the seismic performance of a precast shear wall with a new bundled connection under a high axial compressive ratio, three full-scale precast short-limb shear walls and one full-scale cast-in-place short-limb shear wall were ...
Xiaohui Zhang   +6 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

A dynamic convergence control scheme for the solution of the radial equilibrium equation in through-flow analyses [PDF]

open access: yes, 2010
One of the most frequently encountered numerical problems in scientific analyses is the solution of non-linear equations. Often the analysis of complex phenomena falls beyond the range of applicability of the numerical methods available in the public ...
Templalexis, I.   +3 more
core   +1 more source

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