Results 51 to 60 of about 189,459 (306)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Local stability analysis of axial compression members with welded box-shaped section of Q690 high strength steel

上海师范大学学报. 自然科学版
High strength steel welded box-shaped axial compression members have been widely used in steel structure engineering. In this paper, ANSYS analysis software was adopted to establish a finite element model considering the local geometrical initial defect ...
ZHAO Chuandou, YANG Yonghua
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Study on Creep Compression Characteristics of Pressure-Bearing Graded Crushed Rock

Buildings
To study the creep compression characteristics and evolution mechanism of pressure-bearing graded crushed rock under constant load. Creep compression tests of crushed rock were conducted using the self-developed confined compression test system under ...
Yu Tian, Mei Zhi, Jie Zhou, Pengfei Ji, Shitong Peng   +4 more
doaj   +1 more source

Study on the Axial Compression Postbuckling Similitude Model of the Stiffened Cylindrical Shell with Dimple Imperfections

Advances in Civil Engineering, 2021
The body of the new-type dry gas holder is a large stiffened cylindrical shell. Limited by the test site and economic conditions, the buckling characteristics of such holders are generally studied through scale model experiments.
Jiawei Ding, Xinkui Xing, Wei Yu, Wanxu Zhu   +3 more
doaj   +1 more source

Harmonic chirp imaging method for ultrasound contrast agent [PDF]

, 2005
Coded excitation is currently used in medical ultrasound to increase signal-to-noise ratio (SNR) and penetration depth. We propose a chirp excitation method\ud for contrast agents using the second harmonic component of the response.
Associate Member, Ayache Bouakaz, Chien Ting Chin, Jerome M. G. Borsboom, Michel Versluis, Nico De Jong   +5 more
core   +5 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Thick Walled Multiple Opening Reinforced Concrete Conduits [PDF]

, 1972
The Department of The Army Corps of Engineers, Engineering Division, Civil Works, Contract No.
Gamble, W.L., Mohraz, Bijan, Ryan, M.O., Salem, M.H.   +3 more
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Performance of externally CFRP confined RC columns with changes in thickness of the wrap, slenderness of the column and shape of the section

MATEC Web of Conferences, 2012
The present study deals with the analysis of experimental results, in terms of load carrying capacity and strains, obtained from tests on reinforced concrete (RC) columns, strengthened with external carbon fiber reinforced polymer (CFRP) sheets.
Gahmous M., Benzaid R., Chikh N., Mesbah H.   +3 more
doaj   +1 more source