Results 31 to 40 of about 48,340 (267)

ANALYSIS OF EXPERIMENTAL DATA OF TESTING OF SOILS BY THE METHOD OF THREE-AXIAL COMPRESSION

Construction and Architecture, 2021
The article analyzes the data obtained during soil testing in the ASIS-1 measuring and computational complex, the GT 1.3.1-05 triaxial compression device, conclusions are drawn about the possibility of determining the structural strength of soils in this device, graphic results are analyzed, and conclusions are drawn.
Yuliya Matvienko, Oksana Osipova
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Bearing capacity of UHPC-filled circular steel tube short column under axial compression

Građevinar
This study establishes a predictive formula for the axial compression bearing capacity of Ultra High Performance Concrete (UHPC) filled circular steel tube (circular UHPCFST) short columns. The basis for establishing this formula is the derivation method
Shengbing Fang
doaj   +1 more source

Local stability analysis of axial compression members with welded box-shaped section of Q690 high strength steel

上海师范大学学报. 自然科学版
High strength steel welded box-shaped axial compression members have been widely used in steel structure engineering. In this paper, ANSYS analysis software was adopted to establish a finite element model considering the local geometrical initial defect ...
ZHAO Chuandou, YANG Yonghua
doaj   +1 more source

Axial Compressive Performance of Steel-Reinforced UHPC-Filled Square Stainless-Steel Tube

Buildings, 2022
To study the axial compression performance of a steel-reinforced ultra-high-performance concrete-filled square stainless-steel tube (SR-UHPCFSSST), eight specimens were designed with different length-to-diameter ratios and skeleton contents, and axial ...
Zhan Cheng, Junhua Li, Chuangchuang Wu, Tianyi Zhang, Guofeng Du   +4 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Research on Effect of Axial Compression Ratio on Corrugated Steel Plate-concrete Composite Shear Wall

工程科学与技术, 2020
In order to study the influence of axial compression ratio on corrugated steel plate-concrete composite shear walls(SPCSW), ABAQUS finite element software with different axial compression ratio was used for the nonlinear analysis of vertical corrugated ...
Wei WANG, Yujian LIANG, Zhaoxing XIANG, Jun WANG   +3 more
doaj  

AXIAL COMPRESSION TESTING OF CARBON FIBERS

, 2019
In this study, the axial compression strength of carbon fiber multifilament has been determined on a series PAN-based carbon fibers using bundle compression test similar to the compression measurement of unidirectional laminated composites. This test allows for rapid response and utilizes smaller amounts of material for initial screening testing.
openaire   +3 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source