Results 21 to 30 of about 48,340 (267)

Research on axial compression performance test and bearing capacity calculation method of newly assembled hollow lattice wallboard

open access: yesFrontiers in Materials
With the great development of the construction industry, prefabricated building components have been greatly developed. To study the compressive performance of the new wallboard, the axial compression performance test of six full-scale new lattice ...
Yunlin Liu   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Seismic Behavior of Short Concrete Columns with Prestressing Steel Wires

open access: yesAdvances in Materials Science and Engineering, 2014
The seismic behavior of short circular reinforced concrete columns was studied by testing seven columns retrofitted with prestressing steel wire (PSW), subjected to combined constant axial compression and lateral cyclic load.
Deng Zong-Cai, Jumbe R. Daud, Li Hui
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Experimental Study on the Seismic Performance of Insulated Single-Sided Composite Shear Walls under Different Shear Spans and Axial Compression Ratios

open access: yesAdvances in Civil Engineering
The new insulated single-sided composite shear wall (NISCSW) composition involves setting a precast wall panel on one side and an insulation panel on the other side, with a middle cavity for casting concrete.
Qiang Sun   +5 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Research on Bearing Capacity of Angle Steel Transmission Tower Subject to Parallel Reinforcement by Fitting Channel Steel

open access: yes南方能源建设, 2023
[Introduction] The existing angle steel transmission tower has been running for many years, and the structural damage leads to the reduction of service performance.
Jinghui LI   +4 more
doaj   +1 more source

Behavior of welded gabion boxes in axial compression tests

open access: yesSoils and Rocks
This article presents the results of innovative laboratory tests conducted on different types of cubic gabion boxes, each with approximate edge length of 1 m. The tests evaluated both confined and unconfined boxes subjected to compression stresses. In addition to the confinement factor, the experimental variables included the type of mesh, the presence
Gisleine Coelho Campos   +2 more
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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