Results 51 to 60 of about 1,307,206 (279)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

On Geometric Characteristics of an n-Dimensional Simplex

open access: yesМоделирование и анализ информационных систем, 2011
We prove and discuss some propositions for geometric characteristics of an n-dimensional simplex. Also we note the connection with linear interpolation on the cube [0; 1]^n.
M. V. Nevskii
doaj  

Axial Compression Prediction and GUI Design for CCFST Column Using Machine Learning and Shapley Additive Explanation

open access: yesBuildings, 2022
Axial bearing capacity is the key index of circular concrete-filled steel tubes (CCFST). A hybrid PSO-ANN model consisting of an artificial neural network (ANN) optimized with particle swarm algorithm (PSO) was proposed to reliably and accurately predict
Xuerui Liu, Yanqi Wu, Yisong Zhou
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Effect of Solid Properties on Axial Liquid Dispersion in Bubble Column

open access: yesAl-Khawarizmi Engineering Journal, 2012
Experiments were conducted to study axial liquid dispersion coefficient in slurry bubble column of 0.15 m inside diameter and 1.6 m height using perforated plate gas distributor of 54 holes of a size equal to 1 mm diameter and with a 0.24 free area of ...
Ali Raad Mohammed Jawad
doaj   +2 more sources

Optic Disc-Fovea Distance, Axial Length and Parapapillary Zones. The Beijing Eye Study 2011. [PDF]

open access: yesPLoS ONE, 2015
To measure the distance between the optic disc center and the fovea (DFD) and to assess its associations.The population-based cross-sectional Beijing Eye Study 2011 included 3468 individuals aged 50+ years.
Rahul Arvo Jonas   +6 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Cell Dimension and Proportion of Acacia aulacocarpa Wood in Axial and Radial Directions from Gunung Kidul, Yogyakarta

open access: yesJurnal Ilmu Pertanian Indonesia
The information related anatomical characteristics (cell dimension and proportion) of Acacia aulacocarpa is still limited also for its axial and radial variations.
Viola Elizabeth, Fanny Hidayati
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

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