Results 31 to 40 of about 175,376 (264)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

NUMERICAL INVESTIGATION OF THE CO-AXIAL IMPINGING JETS WITH VARIOUS DIAMETER RATIOS

Journal of Enhanced Heat Transfer, 2012
A predictive theory is presented which is capable of providing quantitative results for the heat transfer in impinging co-axial jets for the turbulent flow regime. The numerical solution is performed by making use of the CFX software package which discretizes the solution domain into quadrilateral elements.
Celik, Nevin, Bettenhausen, Daniel W.
openaire   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Correlation between axial and coronal common bile duct diameters in computed tomography: a retrospective study of 1064 patients

The Egyptian Journal of Radiology and Nuclear Medicine
Background The measurement of the common bile duct (CBD) diameter is essential for evaluating bile duct pathologies. The axial plane of computed tomography (CT) images is the established method for CBD diameter measurement.
Adisak Kasemassawachanont, Natinee Chuangsuwanich, Wanicha Lertpipopmetha, Nutthanun Panrong, Kittipott Thusneyapan, Sasima Tongsai, Napakadol Noppakunsomboon, Rathachai Kaewlai   +7 more
doaj   +1 more source

Orthogonal Analysis of Axial Bearing Capacity of Short Columns Reinforced by Circular Steel Tube and Ultra High Performance Concrete with Coarse Aggregate

Renmin Zhujiang, 2021
This paper analyzes the influence of outer diameter of steel tube, wall thickness of steel tube, steel strength and concrete strength on the axial bearing capacity of short columns reinforced by circular steel tube and ultra high performance concrete ...
TANG Jiajun, WANG Tan, LI Jiuyang
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Comparative evaluation of implant designs: Influence of diameter, length, and taper on stress and strain in the mandibular segment-A three-dimensional finite element analysis

Journal of Pharmacy and Bioallied Sciences, 2019
Introduction: Success or failure of dental implants depends on the amount of stress transferred to the surrounding bone. Increased amount of loading to the bone through implant cause failure, whereas decrease in the amount of loading to the bone causes ...
Gowthama Raaj, Pulliappan Manimaran, Chandran Dhinesh Kumar, Duraisamy Sai Sadan, Mathivanan Abirami   +4 more
doaj   +1 more source

Axial Compression Prediction and GUI Design for CCFST Column Using Machine Learning and Shapley Additive Explanation

Buildings, 2022
Axial bearing capacity is the key index of circular concrete-filled steel tubes (CCFST). A hybrid PSO-ANN model consisting of an artificial neural network (ANN) optimized with particle swarm algorithm (PSO) was proposed to reliably and accurately predict
Xuerui Liu, Yanqi Wu, Yisong Zhou
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Sensitivity analysis of factors influencing the reliability of reinforced concrete columns strengthened with Fabric-Reinforced cementitious matrix

Tạp chí Khoa học và Công nghệ
This paper presents a sensitivity analysis of key factors influencing the reliability of reinforced concrete columns strengthened with Fabric-Reinforced Cementitious Matrix (FRCM) with carbon fabric.
Dang Cong-Thuat, Le Khanh Toan, Pham My, Dinh Ngoc Hieu   +3 more
doaj   +1 more source