Results 81 to 90 of about 12,991 (254)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Effect of variable viscosity and wall porosity on the transport of chemically active solute in a three-layered blood flow model

Alexandria Engineering Journal
The rheology of blood flow is more complex in microvessels. Because of the accumulation of blood cells (RBCs) at the center of the axis, it behaves as Casson fluid in the core region, while in the absence of blood particles, it behaves as a Newtonian ...
Ajith M., Sachin Shaw, Sudip Debnath
doaj   +1 more source

Radial and axial dispersion of the liquid phase in a KATAPAK-S¿ structure: Experiments vs CFD simulations

, 2001
The radial, and axial, liquid-phase dispersion within the catalytically packed criss-crossing sandwich structures of KATAPAK-S has been studied experimentally with the use of computational fluid dynamics (CFD).
van Baten, J.M., Ellenberger, J., van Baten, J. M., Krishna, R.   +3 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Particle Dispersion Behaviors of Dense Gas-Particle Flows in Bubble Fluidized Bed

Advances in Mechanical Engineering, 2013
An Euler-Euler two-fluid model incorporating a developed momentum transfer empirical coefficient is developed to study the particle dispersion behaviors of dense gas-particle flows in gas-fluidization reactor.
Sihao Lv, Guohui Li, Xue Liu
doaj   +1 more source

Articolo selezionato come articolo d copertina di Physics of Fluids, April 2018

, 2018
A well-known limitation of hydrodynamic chromatography arises from the synergistic interaction between transverse diffusion and streamwise convection, which enhances axial dispersion through the Taylor-Aris mechanism.
M Giona, A. Adrover, S. Cerbelli
core  

Modeling of protein breakthrough performance in cryogel columns by taking into account the overall axial dispersion.

, 2009
A model considering the overall axial dispersion for describing protein adsorption and breakthrough in monolithic cryogel beds has been developed.
Junxian Yun, Bo Mattiasson, Yun, Junxian, Kirsebom, Harald, Galaev, Igor, Mattiasson, Bo, Igor Yu Galaev, Harald Kirsebom   +7 more
core   +1 more source

Mixing and axial dispersion in Taylor–Couette flows: the effect of the flow regime [PDF]

, 2016
The paper focuses on mixing properties of different Taylor–Couette flow regimes and their consequence on axial dispersion of a passive tracer. A joint approach, relying both on targeted experiments and numerical simulations, has been used to investigate ...
Charton, Sophie, Nemri, Marouan, Climent, Éric   +2 more
core   +1 more source