Results 91 to 100 of about 694,679 (300)

Cone mosaic in eyes with varied axial length using adaptive optics scanning laser ophthalmoscopy

Photodiagnosis and Photodynamic Therapy
Background: Abnormalities in cone photoreceptor topography are closely associated with the development of various ocular diseases, including axial myopia.
Wen-Da Zhou, Li Dong, Han-Xu Shi, Rui-Heng Zhang, Yu-hang Yang, Han-qing Zhao, Yi-Tong Li, Chu-Yao Yu, He-Yan Li, Hao-Tian Wu, Lei Shao, Wen-Bin Wei   +11 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

A comparative study of complications of cataract surgery with phacoemulsification in eyes with high and normal axial length

Advanced Biomedical Research, 2012
Background: This study performed to assess the safety of cataract extraction with phacoemulsification and intraocular lens (IOL) implantation in patients with high axial length compared with patients with normal axial length.
Hamid Fesharaki, Alireza Peyman, Mehdi Rowshandel, Mohammadreza Peyman, Pegah Alizadeh, Mohammadreza Akhlaghi, AliReza Ashtari   +6 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Changes in Axial Length and Refractive Profile in Different Illumination: A Comparative Study to Understand the Impact of Myopia Control

Delhi Journal of Ophthalmology
Purpose: The purpose of the study was to evaluate and compare the changes in axial length and refractive profile in myopic patients exposed with different illumination.
Ritesh Kumar Chaurasiya, Shambhavi Vishwas, Kajal Kasana, Lokesh Chauhan, Pradeep Agarwal   +4 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Ciliary muscles contraction leads to axial length extension —— The possible initiating factor for myopia [PDF]

, 2023
Peng Zhou, Dandan Wang, Lei Fan, Lin Yang, Mingwei Zhao   +4 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Thermally activated magnetization reversal in monoatomic magnetic chains on surfaces studied by classical atomistic spin-dynamics simulations

, 2010
We analyze the spontaneous magnetization reversal of supported monoatomic chains of finite length due to thermal fluctuations via atomistic spin-dynamics simulations. Our approach is based on the integration of the Landau-Lifshitz equation of motion of a
Aharoni A, David S G Bauer, Khajetoorians A A Lounis S Chilian B Costa A T Zhou L Mills D L Wiebe J Wiesendanger R, Lazarovits B, Lounis S Costa A T Muniz R B Mills D L, Phivos Mavropoulos, Samir Lounis, Skubic B, Stefan Blügel, Šipr O, Šipr O   +10 more
core   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source