Results 101 to 110 of about 707,049 (349)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Internal fibre length concentration in a pressure screen [PDF]

open access: yes, 2007
Localised axial consistency profiles within a pressure screen of a Pinus Radiata kraft pulp are reported. Axial Samples were also analysed using a Kajaani FS-200 to obtain fibre length distribution data.
Atkins, Martin John   +2 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Zero Sound and First Sound in a Disk-Shaped Normal Fermi gas

open access: yes, 2009
We study the zero sound and the first sound in a dilute and ultracold disk-shaped normal Fermi gas with a strong harmonic confinement along the axial direction and uniform in the two planar directions.
A. L. Fetter   +11 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A comparative study of complications of cataract surgery with phacoemulsification in eyes with high and normal axial length

open access: yesAdvanced Biomedical Research, 2012
Background: This study performed to assess the safety of cataract extraction with phacoemulsification and intraocular lens (IOL) implantation in patients with high axial length compared with patients with normal axial length.
Hamid Fesharaki   +6 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Cone mosaic in eyes with varied axial length using adaptive optics scanning laser ophthalmoscopy

open access: yesPhotodiagnosis and Photodynamic Therapy
Background: Abnormalities in cone photoreceptor topography are closely associated with the development of various ocular diseases, including axial myopia.
Wen-Da Zhou   +11 more
doaj   +1 more source

Comparison of IOLMaster® and A-Scan Ultrasound: Change in Axial Length After Vitrectomy in Macular Disease [PDF]

open access: bronze, 2009
Seung Won Lee   +5 more
openalex   +1 more source

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