Results 51 to 60 of about 2,506,179 (296)

Association between ocular axial length and anthropometrics of Asian adults

BMC Research Notes, 2021
Objective The purpose of this study is to analyze axial length, body height, hand length, and foot length to find new factors that predict myopia and to identify gender differences as one of the factors of high myopia.
Ari Shinojima, Toshihide Kurihara, Kiwako Mori, Yujiro Iwai, Akiko Hanyuda, Kazuno Negishi, Hidemasa Torii, Kazuo Tsubota   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Axial length in unilateral idiopathic central serous chorioretinopathy [PDF]

International Journal of Ophthalmology, 2016
AIM: To evaluate the axial length (AXL) in unilateral idiopathic central serous chorioretinopathy (CSC). METHODS: This retrospective case-control study was comprised of a consecutive case series of 35 patients with acute unilateral idiopathic CSC, and ...
Hoseok Moon, Dae Yeong Lee, Dong Heun Nam   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Keratoconus Association with Axial Myopia

, 2012
Pur po se: To study the relationship between keratoconus and axial myopia and also to compare anterior chamber depth, axial length and posterior segment length in normal eyes and keratoconic eyes using ultrasound biometry.
Alime Güneş
core   +1 more source

Ocular axial length and its associations in Chinese: the Beijing Eye Study. [PDF]

PLoS ONE, 2012
To investigate the normative data of ocular axial length and its associations in Chinese.The population-based Beijing Eye Study 2011 is a cross-sectional study performed in Greater Beijing.
Guo Yin, Ya Xing Wang, Zhi Yun Zheng, Hua Yang, Liang Xu, Jost B Jonas, Beijing Eye Study Group   +6 more
doaj   +1 more source

Pterygium Is Related to Short Axial Length

Cornea, 2019
Purpose: To test the hypothesis that pterygium presents with both refractive and anatomical changes, especially short axial length. Methods: A retrospective, hospital-based cross-sectional study included 521 eyes from 521 patients who were enrolled through a community survey by ...
Zhang, Li Mei, Lu, Yang, Gong, Lan
openaire   +3 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Ocular axial length and its associations: A systematic review

African Vision and Eye Health
Background: Axial length is key in determining the underlying cause of refractive errors, including myopia. It is essential for assessing myopic progression or risk in patients. Aim: To systematically evaluate associations between ocular axial length and
Andrew T. Chikara, Tanya Evans, Solani D. Mathebula   +2 more
doaj   +1 more source