Results 41 to 50 of about 236,478 (267)
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The axial compressive performance of steel-reinforced concrete columns with monosymmetric cross-shaped steel (SRCC-MCS) was investigated in this study.
Jipeng Yu +3 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Axial Ratio of the Projected Polarization Ellipse [PDF]
The axial ratio of the polarization ellipse of a radio wave is often evalp,ated using a crossed-dipole antenna system placed in a horizontal plane. The axial ratio of the ellipse as deduced from the responses of the two antennas should correspond to the axial ratio of the ellipse in the wave-front as projected onto the horizontal plane. When one of the
openaire +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Axial Length–Disc Area Ratio in Esotropic Amblyopia [PDF]
Hyperopia is a risk factor for esotropia and amblyopia. A previous study indicated that disc areas (DAs) are reduced in patients with amblyopia.To determine if there is a difference in the relative size of the optic disc in hyperopic eyes without strabismus or amblyopia compared with esotropic and amblyopic eyes, the relationship of axial length (AXL ...
openaire +2 more sources
Reconfigurable Axial Ratio in Compact GNSS Antennas [PDF]
A new adaptive technique for steering the direction of minimum axial ratio (AR) (<1 dB) toward the reflected or jamming signal is proposed for global navigation satellite systems antennas. It relies on simple, low cost commercially available circularly polarized antenna elements without influencing their gain.
A. Narbudowicz +2 more
openaire +3 more sources

