Results 171 to 180 of about 13,446 (222)

The Genetics of Ankylosing Spondylitis and Axial Spondyloarthritis [PDF]

open access: yesRheumatic Disease Clinics of North America, 2012
Ankylosing spondylitis (AS) and spondyloarthritis are strongly genetically determined. The long-standing association with HLA-B27 is well described, although the mechanism by which that association induces AS remains uncertain. Recent developments include the description of HLA-B27 tag single nucleotide polymorphisms in European and Asian populations ...
Philip Robinson, Matthew A Brown
exaly   +7 more sources

The impact of ankylosing spondylitis/axial spondyloarthritis on work productivity [PDF]

open access: yesBest Practice and Research in Clinical Rheumatology, 2015
Ankylosing spondylitis (AS) is a chronic inflammatory condition that has a significant impact on the quality of life and work productivity. New classification criteria have enabled earlier diagnosis of this condition. However, work productivity is an important issue that is still often overlooked during clinical assessments and consultations.
Jane Martindale, John Goodacre
exaly   +4 more sources

What are axial spondyloarthritis and ankylosing spondylitis? [PDF]

open access: yes, 2016
Ankylosing spondylitis (AS) is a chronic inflammatory arthritis affecting mainly the sacroiliac joints and spine, resulting in pain, stiffness, and reduced movement. AS has a major negative impact on patients’ quality of life. AS is part of a larger group of related spondyloarthritis (SpA) conditions and patients with AS often have extra-articular ...
Stefan Siebert   +2 more
openaire   +2 more sources

TNFα-inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritis [PDF]

open access: yesClinical Pharmacist, 2017
Spondyloarthropathy refers to a group of articular inflammatory diseases that share common genetic, clinical and radiological features in addition to their association with human leucocyte antigen (HLA)-B27 antigen. The aim of therapeutic management of patients with spondyloarthritis is to improve quality of life, control the symptoms of articular ...
Scotti N.   +9 more
openaire   +3 more sources

Axial disease in psoriatic arthritis and ankylosing spondylitis: a critical comparison

Nature Reviews Rheumatology, 2018
Ankylosing spondylitis (AS) was first identified in the late 17th century. 250 years later, inflammatory spine disease was recognized to be one of the patterns of psoriatic arthritis (PsA). Isolated spondylitis is rare among patients with PsA, occurring in less than 5% of patients; however, many patients with PsA have axial disease that is concurrent ...
Robert Inman   +2 more
exaly   +3 more sources

Classification criteria for psoriatic arthritis and ankylosing spondylitis/axial spondyloarthritis

Best Practice and Research in Clinical Rheumatology, 2010
The concept of spondyloarthritides (or spondyloarthropathies, SpAs) that comprises a group of interrelated disorders has been recognised since the early 1970s. While the European Spondyloarthropathy Study Group (ESSG) criteria and the Amor criteria have been developed to embrace the entire group of SpAs, new criteria for psoriatic arthritis have been ...
Martin Rudwaleit, William Taylor
exaly   +3 more sources

The epidemiology of ankylosing spondylitis, axial spondyloarthritis, and back pain [PDF]

open access: yes, 2016
Low back pain is a leading cause of disability worldwide. The prevalence of inflammatory back pain (IBP) has been calculated to be in the range 8–15% in a UK primary care population and 5–7% in a US population-based cohort. IBP rates are significantly higher in patients with psoriasis, uveitis, or inflammatory bowel disease than the general population.
Stefan Siebert   +2 more
openaire   +2 more sources

MRI of the axial skeletal manifestations of ankylosing spondylitis

Clinical Radiology, 2004
Magnetic resonance imaging (MRI) is a valuable tool in the imaging and assessment of patients with ankylosing spondylitis. MRI can demonstrate the acute and chronic changes of sacroiliitis, osteitis, discovertebral lesions, disc calcifications and ossification and arthopathic lesions, which characterize the disease, as well as the complications, which ...
D S, Levine, S M, Forbat, A, Saifuddin
openaire   +2 more sources

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