Results 141 to 150 of about 3,661,776 (333)
Biodynamics of the seated human body with dual-axis excitation: nonlinearity and cross-axis coupling
, 2012 The apparent mass of the seated human body and the transmissibility to the upper-body (i.e., the spine and the pelvis) during vertical vibration excitation have been reported to have resonance frequencies around 5 Hz.
Zheng, Guangtai
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
, 2008 The mriga of Shiva in stone sculptures from Tamil Nadu appears to be either an antlerless young spotted deer or an adult spotted mouse deer. Spotted deer hardly play an active role in narrative reliefs; rare exceptions are the Story of the Two Deer and the Story of Rama Hunting the Golden Deer as told in the epic Ramayana.
openaire +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Gut–liver axis: barriers and functional circuits
Nature reviews: Gastroenterology & hepatology, 2023 O. Pabst +5 more
semanticscholar +1 more source
Optimal Design of a Micro Vertical Axis Wind Turbine for Sustainable Urban Environment [PDF]
The need for sustainable energy sources becomes greater each year due to the continued depletion of fossil fuels and the resulting energy crisis. Solutions to this problem are potentially in the form of wind turbines, for sustainable urban environment ...
Park, Kyooseon
core +3 more sources
Osteomyelitis of the Odontoid Process: A Literature Review and Recommendations
Journal of Orthopaedic Case ReportsIntroduction: Odontoid osteomyelitis (OOM) is a rare clinical entity that requires a high degree of suspicion for diagnosis. A literature review was conducted to make recommendations for early diagnosis and best practices in the management of OOM ...
Justin Choi, Krishnamurthi Sundaram
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Foundations of Computing and Decision Sciences, 2018 Continuous integration and continuous software deployment depend on the mix of automated and manual activities. The automated build and test processes are often intertwined with manual reviews and bug-fixing activities.
Staron Miroslaw +3 more
doaj +1 more source