Results 121 to 130 of about 5,247,612 (307)

Focal axis resolver for offset reflector antennas [PDF]

, 1983
Method and apparatus for determining the focal axis of an asymmetrical antenna such as an offset paraboloid reflector whose physical rim is not coincident with the boundary of the electrical aperture but whose focal point is known is provided.
Schmidt, R. F.
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Sex-dependent effects of a high-fat diet on the hypothalamic response in mice

Biology of Sex Differences
Sex differences in rodent models of diet-induced obesity are still poorly documented, particularly regarding how central mechanisms vary between sexes in response to an obesogenic diet.
Virginie Dreux, Candice Lefebvre, Charles-Edward Breemeersch, Colin Salaün, Christine Bôle-Feysot, Charlène Guérin, Pierre Déchelotte, Alexis Goichon, Moïse Coëffier, Ludovic Langlois   +9 more
doaj   +1 more source

Cupric chloride CuCl2 as an S=1/2 chain multiferroic

, 2010
Magnetoelectric properties were investigated for an S=1/2 chain antiferromagnet CuCl2, which turns out to be the first example of non-chalcogen based spiral-spin induced multiferroics.
H. Matsui, H. Murakawa, S. Ishiwata, S. Seki, T. Hasegawa, T. Kurumaji, T. Nagamiya, Y. Kaneko, Y. Tokunaga, Y. Tokura   +9 more
core   +1 more source

Axis axis, the spotted deer

, 2008
The mriga of Shiva in stone sculptures from Tamil Nadu appears to be either an antlerless young spotted deer or an adult spotted mouse deer. Spotted deer hardly play an active role in narrative reliefs; rare exceptions are the Story of the Two Deer and the Story of Rama Hunting the Golden Deer as told in the epic Ramayana.
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Evolution of Spin Direction of Accreting Magnetic Protostars and Spin-Orbit Misalignment in Exoplanetary Systems: II. Warped Discs

, 2010
Magnetic interactions between a protostar and its accretion disc tend to induce warping in the disc and produce secular changes in the stellar spin direction, so that the spin axis may not always be perpendicular to the disc.
Alencar, Aly, Aly, Bate, Bouvier, Bouvier, Chatterjee, Dong Lai, Eggleton, Fabrycky, Francois Foucart, Holman, Juric, Lai, Lai, Lai, Lin, Lodato, Long, Lovelace, Lubow, Lubow, Matt, McKee, Nagasawa, Ogilvie, Ogilvie, Papaloizou, Papaloizou, Papaloizou, Pfeiffer, Press, Pringle, Romanova, Schlaufman, Shakura, Shu, Terquem, Terquem, Triaud, Winn, Wu, Wu   +42 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Osteomyelitis of the Odontoid Process: A Literature Review and Recommendations

Journal of Orthopaedic Case Reports
Introduction: Odontoid osteomyelitis (OOM) is a rare clinical entity that requires a high degree of suspicion for diagnosis. A literature review was conducted to make recommendations for early diagnosis and best practices in the management of OOM ...
Justin Choi, Krishnamurthi Sundaram
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source