Results 101 to 110 of about 3,661,776 (333)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Neospora caninum is a cause of perinatal mortality in axis deer (Axis axis)
Veterinary Parasitology, 2014 Neospora caninum is a worldwide distributed protozoan that may cause neuromuscular disease in dogs and reproductive failure in domestic and wild ruminants. One axis fawn (Axis axis) and four neonates from the same deer herd died at a zoo in Argentina within a four-month period.
Basso, Walter +5 more
openaire +4 more sources
Nature Communications, 2018 Long-range GABAergic hippocampal neurons project to cortical and subcortical areas, while vasoactive intestinal peptide (VIP+) interneurons can inhibit other GABAergic neurons.
Ruggiero Francavilla +9 more
doaj +1 more source
Force calculation of the process of briquetting powder, chip and other bulk materials
Литьë и металлургия, 2019 The work is devoted to solving the axisymmetric problem of the theory of pressing porous bodies with practical application in the form of force calculation of metallurgical processes of briquetting small fractional bulk materials: powder, chip ...
O. M. Dyakonov
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Medial Axis and Singularities [PDF]
The Journal of Geometric Analysis, 2017 This paper is devoted to the study of the medial axes of sets definable in polynomially bounded o-minimal structures, i.e. the sets of points with more than one closest point with respect to the Euclidean distance. Our point of view is that of singularity theory.
Lev Birbrair, Maciej P. Denkowski
openaire +3 more sources
Coluna/Columna, 2011 OBJETIVO: Analisar uma série de pacientes com fraturas de odontoide do tipo III, instáveis, tratados cirurgicamente. MÉTODOS: Análise retrospectiva de uma série de 5 casos consecutivos de pacientes com fratura de odontoide do tipo III, submetidos a ...
Alan Robert Wieczorek +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Numerical simulation in vertical wind axis turbine with pitch controlled blades [PDF]
, 2012 Wind energy is more and more used as a renewable energy source character. The present wind turbine is a small one which allows to be used on roofs or in gardens to light small areas like publicity boards, parking, roads or for water pumping, heating ...
SIMONET, Sophie +3 more
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