Results 81 to 90 of about 1,987,507 (267)

Rebaudioside D decreases adiposity and hepatic lipid accumulation in a mouse model of obesity

Scientific Reports
Overconsumption of added sugars has been pointed out as a major culprit in the increasing rates of obesity worldwide, contributing to the rising popularity of non-caloric sweeteners.
Arianne Morissette, Alice de Wouters d’Oplinter, Diana Majolli Andre, Marilou Lavoie, Bruno Marcotte, Thibault V. Varin, Jocelyn Trottier, Geneviève Pilon, Martin Pelletier, Patrice D. Cani, Olivier Barbier, Vanessa P. Houde, André Marette   +12 more
doaj   +1 more source

The Mitochondrial Permeability Transition Pore in Platelets: Mechanisms, Physiological Roles, and Therapeutic Perspectives

Antioxidants
Platelets have long been known to be critically involved in hemostasis and thrombosis. However, platelets are also recognized as metabolically active cells that require well-regulated mitochondrial function to support their multiple functions in ...
Chiara Lonobile, Alessia Di Nubila, Rosa Simone, Matilda Hushi, Silvia Stella Barbieri   +4 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Challenges in Diagnosis and Management of Crohn's Disease in Bangladesh With Long Term Follow‐Up

Clinical Case Reports
Crohn's disease (CD) is a chronic autoimmune inflammatory bowel disease (IBD) with significant diagnostic and therapeutic challenges. We reported a case of a 20‐year‐old Bangladeshi male with an 8‐month history of severe upper abdominal pain, bowel ...
Imtiaz Abdullah, Imran Hasan, Mantaka Rahman, Shoma Hayat, Nowshin Papri, Nusrat Fatema, Ahmedul Kabir, Zhahirul Islam   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impact of endoscopic ultrasound-guided fine needle aspiration of small lymph nodes

Journal of Digestive Endoscopy, 2016
Background: There is very limited literature on results of fine needle aspiration (FNA) of small (defined as ≤1 cm at long and short axis) lymph nodes, particularly in the setting of pyrexia of unknown origin (PUO).
Narendra S. Choudhary, Rinkesh Kumar Bansal, Rajesh Puri, Vijay Bodh, Gaurav Kumar Patil, Mukesh Nasa, Rajiv Ranjan Singh, Haimanti Sarin, Mridula Guleria, Randhir Sud   +9 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Evaluation of the influence of atlantoaxial transverse ligament on stability of atlantoaxial complex fracture using 3D finite element method

Zhongguo linchuang yanjiu
Objective To analyze and compare the effects of transverse ligament injury on the stability and stress distribution of atlantoaxial complex fractures using 3D finite element method. Methods A male volunteer with a normal cervical spine was selected.
HUANG Kai, LIU Chao
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source