Results 71 to 80 of about 3,661,776 (333)
Role of the CCL2‐CCR2 signalling axis in cancer: Mechanisms and therapeutic targeting
Cell Proliferation, 2021 The chemokine ligand CCL2 and its receptor CCR2 are implicated in the initiation and progression of various cancers. CCL2 can activate tumour cell growth and proliferation through a variety of mechanisms.
Maosen Xu +4 more
semanticscholar +1 more source
Gut microbiota and its metabolic products in acute respiratory distress syndrome
Frontiers in ImmunologyThe prevalence rate of acute respiratory distress syndrome (ARDS) is estimated at approximately 10% in critically ill patients worldwide, with the mortality rate ranging from 17% to 39%.
Dong-Wei Zhang +16 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
The gut-liver axis and the intersection with the microbiome
Nature reviews: Gastroenterology & hepatology, 2018 In the past decade, an exciting realization has been that diverse liver diseases — ranging from nonalcoholic steatohepatitis, alcoholic steatohepatitis and cirrhosis to hepatocellular carcinoma — fall along a spectrum.
A. Tripathi +6 more
semanticscholar +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The Angiotensin‐Melatonin Axis [PDF]
International Journal of Hypertension, 2013 Accumulating evidence indicates that various biological and neuroendocrine circadian rhythms may be disrupted in cardiovascular and metabolic disorders. These circadian alterations may contribute to the progression of disease. Our studies direct to an important role of angiotensin II and melatonin in the modulation of circadian rhythms. The brain renin‐
Campos, L.A. +5 more
openaire +3 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Statistical modelling for prediction of axis-switching in rectangular jets [PDF]
, 2013 Rectangular nozzles are increasingly used for modern military aircraft propulsion installations, including the roll nozzles on the F-35B vertical/short take-off and landing strike fighter.
Knowles, Kevin +2 more
core +1 more source
Can antler stage represent an activity driver in axis deer Axis axis? [PDF]
Wildlife Biology, 2019 The aim of this study was to determine the seasonal activity patterns and asynchrony between different antler stages in male axis deer from the Mediterranean island of Rab in Croatia using camera traps. Nine cameras with an infrared motion detection system were used to track animal activity over a 12-month period, 24 hours per day.
Ugarković, Damir +6 more
openaire +2 more sources
Performance evaluation of three cross flow vertical axis wind turbine configurations. [PDF]
, 2009 The performance output of three Vertical Axis Wind Turbine (VAWT) configurations has been evaluated using a two-dimensional Computational Fluid Dynamic (CFD) model. Data has been obtained using a quasi-steady Multi Reference Frame (MRF) approach in which
Rao, H.V. +3 more
core +3 more sources