Results 61 to 70 of about 1,987,507 (267)
Medial Axis and Singularities [PDF]
The Journal of Geometric Analysis, 2017 This paper is devoted to the study of the medial axes of sets definable in polynomially bounded o-minimal structures, i.e. the sets of points with more than one closest point with respect to the Euclidean distance. Our point of view is that of singularity theory.
Lev Birbrair, Maciej P. Denkowski
openaire +3 more sources
Force calculation of the process of briquetting powder, chip and other bulk materials
Литьë и металлургия, 2019 The work is devoted to solving the axisymmetric problem of the theory of pressing porous bodies with practical application in the form of force calculation of metallurgical processes of briquetting small fractional bulk materials: powder, chip ...
O. M. Dyakonov
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Nature Communications, 2018 Long-range GABAergic hippocampal neurons project to cortical and subcortical areas, while vasoactive intestinal peptide (VIP+) interneurons can inhibit other GABAergic neurons.
Ruggiero Francavilla +9 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Coluna/Columna, 2011 OBJETIVO: Analisar uma série de pacientes com fraturas de odontoide do tipo III, instáveis, tratados cirurgicamente. MÉTODOS: Análise retrospectiva de uma série de 5 casos consecutivos de pacientes com fratura de odontoide do tipo III, submetidos a ...
Alan Robert Wieczorek +2 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Folia MorphologicaBACKGROUND: The anatomical relationship between the C2 transverse foramen (TF) and the vertebral artery (VA), particularly at the superior and inferior openings of the C2 TF, is clinically important in upper cervical spine surgery because of the ...
Lixin Tang +10 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source