Results 91 to 100 of about 5,247,612 (307)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Genomic variability of lipooligosaccharide biosynthesis locus and sequence type among Campylobacter jejuni isolated from patients with Guillain-Barré syndrome

Microbiology Spectrum
Lipooligosaccharide (LOS) is a crucial component of the Campylobacter jejuni (C. jejuni) cell membrane that mimics human gangliosides and can induce autoimmune neuropathies like Guillain-Barré syndrome (GBS). Approximately one in 1,000 C.
Md. Abu Jaher Nayeem, Shoma Hayat, Asaduzzaman Asad, Md. Golam Mostafa, Shah Nayeem Faruque, Ruma Begum, Mosabbir Ahmed, Yearul Kabir, Israt Jahan, Zhahirul Islam   +9 more
doaj   +1 more source

Fraturas de odontoide tipo III com necessidade de tratamento cirúrgico: estudo de série de casos e revisão de literatura Fracturas de odontoides tipo III con necesidad de tratamiento quirúrgico: estudio de série de casos y revisión de la literatura Type III odontoid fractures requiring surgical treatment: a case series study and literature review

Coluna/Columna, 2011
OBJETIVO: Analisar uma série de pacientes com fraturas de odontoide do tipo III, instáveis, tratados cirurgicamente. MÉTODOS: Análise retrospectiva de uma série de 5 casos consecutivos de pacientes com fratura de odontoide do tipo III, submetidos a ...
Alan Robert Wieczorek, Marcelo Simoni Simões, Ernani Vianna Abreu   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

PD-1/PD-L1 Axis Downregulation in Guillain-Barré Syndrome: A Potential Mechanism Driving the Autoimmune Pathogenesis

International Journal of Infectious Diseases
Introduction: Guillain-Barré syndrome (GBS), an immune-mediated disorder of the peripheral nervous system characterized by progressive muscle weakness, is often triggered by Campylobacter jejuni infection. Molecular mimicry between C.
Mr Rasel Ahmed, Mrs Israt Jahan, Mrs Pritha Biswash, Miss Mehjabeen Haque, Miss Sarah Khurshid, Mr Jigishu Ahmed, Mr Sayed Akib Hossain, Dr Zhahirul Islam   +7 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Resistome phylodynamics of multidrug-resistant Shigella isolated from diarrheal patients

Microbiology Spectrum
Multi-drug resistance (MDR) in Shigella continues to pose a significant public health challenge, particularly in developing countries. Recent advances in genomics strengthen the surveillance of MDR-pathogens and antimicrobial resistance (AMR) mediators ...
Asaduzzaman Asad, Md. Abu Jaher Nayeem, Md. Golam Mostafa, Ruma Begum, Shah Nayeem Faruque, Suraia Nusrin, Israt Jahan, Shoma Hayat, Zhahirul Islam   +8 more
doaj   +1 more source

THE AXIS DEER (AXIS AXIS ) IN BRIJUNI NATIONAL PARK

Journal of Central European Agriculture, 2008
The axis deer (Axis axis) was imported from Germany and introduced into Brijuni in 1911. Brijuni are a group of islands in the Adriatic Sea along the western coast of the southern peak of the Istrian Peninsula in the Republic of Croatia. In 1983 the area was declared a National Park.
Nikica Šprem, DEAN Blažina, TIHOMIR Florijančić, Tomislav Treer, GRACIANO Prekalj   +4 more
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Dual cathode system for electron beam instruments [PDF]

, 1989
An electron beam source having a single electron optical axis is provided with two coplanar cathodes equally spaced on opposite sides from the electron optical axis.
Bradley, James G., Conley, Joseph M., Wittry, David B.   +2 more
core   +1 more source