Results 111 to 120 of about 2,423,656 (318)

Measurement of neutrino oscillation parameters from muon neutrino disappearance with an off-axis beam [PDF]

open access: yes, 2013
The T2K Collaboration reports a precision measurement of muon neutrino disappearance with an off-axis neutrino beam with a peak energy of 0.6 GeV. Near detector measurements are used to constrain the neutrino flux and cross section parameters.
A. Ereditato   +999 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

PENGGUNAAN PENDEKATAN SATIR PADA IKLAN AXIS #KENAPANGGAK

open access: yesJurnal Ranah Komunikasi, 2018
Media is one of the tools that helped shape how cultural practices develop in the midst of human life, one of which is through advertising. This can be the opposite, developing cultural practices also contribute to how advertising in this case are ...
Indah Wenerda
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Correlation between machining direction, cutter geometry and step-over distance in 3-axis milling: Application to milling by zones. [PDF]

open access: yes, 2012
Computer-Aided Manufacturing (CAM) occupies an increasingly important role in engineering with all it has to offer in terms of new possibilities and improving designer/manufacturer productivity. The present study addresses machining of free-form surfaces
Senatore, Johanna   +3 more
core   +1 more source

“Soft that molds the hard:” Geometric morphometry of lateral atlantoaxial joints focusing on the role of cartilage in changing the contour of bony articular surfaces

open access: yesJournal of Craniovertebral Junction and Spine, 2017
Purpose: The existing literature on lateral atlantoaxial joints is predominantly on bony facets and is unable to explain various C1-2 motions observed.
Prashant Kumar Prasad   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Biodynamics of the seated human body with dual-axis excitation: nonlinearity and cross-axis coupling

open access: yes, 2012
The apparent mass of the seated human body and the transmissibility to the upper-body (i.e., the spine and the pelvis) during vertical vibration excitation have been reported to have resonance frequencies around 5 Hz.
Zheng, Guangtai
core  

Osteomyelitis of the Odontoid Process: A Literature Review and Recommendations

open access: yesJournal of Orthopaedic Case Reports
Introduction: Odontoid osteomyelitis (OOM) is a rare clinical entity that requires a high degree of suspicion for diagnosis. A literature review was conducted to make recommendations for early diagnosis and best practices in the management of OOM ...
Justin Choi, Krishnamurthi Sundaram
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

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