Results 131 to 140 of about 2,423,960 (318)
Timing feedback-inhibition of the male reproductive hormone axis
, 2008 Hormonal methods of male contraception have addressed feedback-inhbition of the cascade of hormones that has evolved to regulate sperm production but high concentrations of testosterone (T) in the blood have not worked satisfactorily.
Gopal Gupta +4 more
core +1 more source
Axis, 2012 A mezopotámiai templomok jellegét, számát, egy-egy település és az egész társadalom életében betöltött szerepüket alapvetően két tényező határozta meg.
Gábor Kalla
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Axis, 2012 Fröhlich Ida – Dobos Károly Dániel (szerk.), Henok könyvei (Ószövetségi Apokrifek 1). Ford.: Dobos Károly Dániel, Fröhlich Ida, Hollós Attila. Piliscsaba: Pázmány Péter Katolikus Egyetem Bölcsészettudományi Kar, 2009. 303 oldal.
József Gátas
doaj
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Vertical axis non-linearities in wavelength scanning interferometry
, 2015 The uncertainty of measurements made on an areal surface topography instrument is directly influenced by its metrological characteristics. In this work, the vertical axis deviation from linearity of a wavelength scanning interferometer is evaluated.
Muhamedsalih, Hussam +6 more
core
Tér és idő: A Papi Törvény és a Szent Sátor
Axis, 2012 Hogy a Papi Író kifejezetten érdeklődik a tér és idő behatárolása iránt, az aligha lehet kétséges: egyrészt a Papi Történetírás kezdete, a híres Gen 1 tökéletesen mutatja, hogy a világ teremtésének rendjében igen fontos a distinkció, a megkülönböztetés (
István Karasszon
doaj
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Control based power smoothing for aggregated vertical axis wind turbines
, 2012 Recently there has been renewed interest in the potential of vertical axis wind turbines (VAWTs), particularly, at very large scale of 10 MW or above owing to their structural simplicity.
Leithead, William +2 more
core