Results 141 to 150 of about 2,423,960 (318)

LSMAT Least Squares Medial Axis Transform

, 2019
The medial axis transform has applications in numerous fields including visualization, computer graphics, and computer vision. Unfortunately, traditional medial axis transformations are usually brittle in the presence of outliers, perturbations and/or ...
Rebain, Daniel, Angles, Baptiste, Peethambaran, Jiju, Tagliasacchi, Andrea, Izadi, Shahram, Valentin, Julien, Vining, Nicholas   +6 more
core   +1 more source

Sex-dependent circadian alterations of both central and peripheral clock genes expression and gut–microbiota composition during activity-based anorexia in mice

Biology of Sex Differences
Rationale Patients with anorexia nervosa (AN) often present sleep disorders and circadian hormonal dysregulation. The role of the microbiota–gut–brain axis in the regulation of feeding behavior has emerged during the last decades but its relationships ...
Colin Salaün, Marine Courvalet, Léna Rousseau, Kévin Cailleux, Jonathan Breton, Christine Bôle-Feysot, Charlène Guérin, Marion Huré, Alexis Goichon, Jean-Claude do Rego, Pierre Déchelotte, David Ribet, Najate Achamrah, Moïse Coëffier   +13 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Az erőszak aspektusai a Munkára, Harcra Kész mozgalom propagandájában — Különös tekintettel a mozgalmat népszerűsítő módszerekre 1948–1951 között

Axis
Tanulmányomban a Munkára, Harcra Kész (MHK) mozgalom propagandáját mutatom be, különös tekintettel a népszerűsítésben lévő erőszak különböző aspektusaira.
Jakab Péter
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Az ellenségkép megváltozott természete — Kristó Nagy István három írása

Axis
Tanulmányomban Kristó Nagy István három írásának vizsgálatát és összehasonlítását tűztem ki célul. A három szöveg mindegyike más-más rendszerben, történelmi helyzetben született, az első és az utolsó között kereken 50 év telt el.
Vári Árpád
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Computational flow field analysis of a Vertical Axis Wind Turbine

The present work has used Computational Fluid Dynamics (CFD) to obtain the flow field characteristics of a novel Vertical Axis Wind Turbine (VAWT). The turbine used in this study features a multi blade design where both a stator and rotor blade array is ...
Colley, Gareth, Mishra, Rakesh
core  

A method for analysing fluid structure interactions on a horizontal axis tidal turbine

, 2011
Free stream tidal turbines are rotating bodies in fast flowing tidal currents, and as such are exposed to fluctuating loads from the surrounding fluid.
Nicholls-Lee, R.F., Boyd, S.W., Turnock, S.R.   +2 more
core  

A szovjet megszállás és következményei Szentesen a levéltári források tükrében

Axis
Tanulmányomban a második világháború végi Szentes mindennapjairól, a front átvonulásáról, a szovjet megszállásról, valamint annak a városban és hozzá csatlakozó külterületein elkövetett atrocitásokról adok áttekintést egészen az 1944-es év végéig, mivel ...
Szabó Dániel
doaj   +1 more source