Results 131 to 140 of about 282,607 (316)

Chick PTPσ regulates the targeting of retinal axons within the optic tectum

, 2002
Chick PTP (cPTP), also known as CRYP, is a receptor-like protein tyrosine phosphatase found on axons and growth cones. Putative ligands for cPTP are distributed within basement membranes and on glial end feet of the retina, optic nerve, and optic tectum,
Aricescu, AR, Aricescu, Alexandru, Rashid-Doubell, F, McKinnell, I, Sajnani, G, Stoker, A   +5 more
core  

Inflammation and Axon Degeneration

, 2005
Axon injury is a significant part of multiple sclerosis (MS) pathology. Postmortem analysis shows that axon injury occurs early in the evolution of the plaque, and the degree of axon injury correlates with the intensity of the inflammatory response ...
Perry, V. Hugh, V. Hugh Perry
core   +1 more source

Bias‐Field Free Single‐Frequency CW‐ODMR of Nitrogen‐Vacancy Centers in Diamond for the Detection of Transient Electrical Signals

Advanced Materials Interfaces, EarlyView.
Simplified quantum sensing technique for the detection of short electrical signals occurring in neuronal signaling or bioinspired technologies. We demonstrate a single frequency continuous‐wave optically detected magnetic resonance (CW‐ODMR) approach to sense signals that can be as short as 0.2 ms.
João Paulo Silva, Orlando D. Cunha, Pedro Magalhães, Filipe Camarneiro, Jana B. Nieder   +4 more
wiley   +1 more source

Corrigendum: Genetic Background Influences the Propagation of Tau Pathology in Transgenic Rodent Models of Tauopathy

Frontiers in Aging Neuroscience, 2020
Tomas Smolek, Tomas Smolek, Veronika Cubinkova, Veronika Cubinkova, Veronika Brezovakova, Bernadeta Valachova, Peter Szalay, Peter Szalay, Norbert Zilka, Norbert Zilka, Santosh Jadhav, Santosh Jadhav   +11 more
doaj   +1 more source

Boundary cap cells constrain spinal motor neuron somal migration at motor exit points by a semaphorin-plexin mechanism

, 2007
In developing neurons, somal migration and initiation of axon outgrowth often occur simultaneously and are regulated in part by similar classes of molecules. When neurons reach their final destinations, however, somal translocation and axon extension are
Mitchell, KJ, Little, GE, Vermeren Matthieu, Kokot Natalie, Cohen, J, Little Graham E, Bron Romke, Andrews William, Cohen James, Andrews, W, Bron, R, Kokot, N, Vermeren, M, Mitchell Kevin J   +13 more
core   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Modelling collective axon growth from in vivo data reveals the importance of physical axon-axon interactions [PDF]

, 2017
International audienceNeurite extension is essential to establish complex neuronal circuits during brain development. Neurons extend their axons in a crowded environment to reach target territories and connect to specific partners.
Descombes, Xavier, Medioni, Caroline, Malandain, Grégoire, Razetti, Agustina, Besse, Florence   +4 more
core  

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Initiating and Growing an Axon

, 2010
The ability of neurons to form a single axon and multiple dendrites underlies the directional flow of information transfer in the central nervous system. Dendrites and axons are molecularly and functionally distinct domains.
Snider, William, Polleux, F.
core   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source