Results 41 to 50 of about 479,230 (336)

MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size

open access: yesNature Communications, 2018
Neurons display extreme degrees of polarization, including compartment-specific organelle morphology. In cortical, long-range projecting, pyramidal neurons (PNs), dendritic mitochondria are long and tubular whereas axonal mitochondria display uniformly ...
Tommy L. Lewis   +4 more
semanticscholar   +1 more source

The Axon-Myelin Unit in Development and Degenerative Disease

open access: yesFrontiers in Neuroscience, 2018
Axons are electrically excitable, cable-like neuronal processes that relay information between neurons within the nervous system and between neurons and peripheral target tissues.
Ruth M. Stassart   +3 more
semanticscholar   +1 more source

Node of Ranvier length as a potential regulator of myelinated axon conduction speed

open access: yeseLife, 2017
Myelination speeds conduction of the nerve impulse, enhancing cognitive power. Changes of white matter structure contribute to learning, and are often assumed to reflect an altered number of myelin wraps. We now show that, in rat optic nerve and cerebral
I. Arancibia‐Carcamo   +5 more
semanticscholar   +1 more source

Detecting rs‐fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Preserved resting‐state functional MRI (rs‐fMRI) networks are typically observed in Disorders of Consciousness (DOC). Despite the widespread use of rs‐fMRI in DOC, a systematic assessment of networks is needed to improve the interpretability of data in clinical practice.
Jean Paul Medina Carrion   +15 more
wiley   +1 more source

Near-IR photometry of disk galaxies: search for nuclear isophotal twist and double bars [PDF]

open access: yes, 1997
We present a near-IR, mainly H band, photometry of 72 nearby disk galaxies. The main goal of the survey was to search for isophotal twist inside their nuclear regions.
Axon, David J.   +2 more
core   +2 more sources

The Distance between N and C Termini of Tau and of FTDP-17 Mutants Is Modulated by Microtubule Interactions in Living Cells

open access: yesFrontiers in Molecular Neuroscience, 2017
The microtubule (MT)-associated protein Tau is a natively unfolded protein, involved in a number of neurodegenerative disorders, collectively called tauopathies, aggregating in neurofibrillary tangles (NFT). It is an open question how the conversion from
Cristina Di Primio   +6 more
doaj   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach   +11 more
wiley   +1 more source

The sound of an axon's growth

open access: yes, 2019
Axons are linear processes of nerve cells that can range from a few tens of micrometers up to meters in length. In addition to external cues, the length of an axon is also regulated by unknown internal mechanisms.
Folz, Frederic   +3 more
core   +2 more sources

Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction [PDF]

open access: yes, 2015
Botulinum neurotoxins (BoNTs) and some animal neurotoxins (-Bungarotoxin, -Btx, from elapid snakes and -Latrotoxin, -Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients.
Duregotti, Elisa   +6 more
core   +2 more sources

Floor plate-derived netrin-1 is dispensable for commissural axon guidance

open access: yesNature, 2017
Netrin-1 is an evolutionarily conserved, secreted extracellular matrix protein involved in axon guidance at the central nervous system midline. Netrin-1 is expressed by cells localized at the central nervous system midline, such as those of the floor ...
C. Dominici   +8 more
semanticscholar   +1 more source

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