Results 31 to 40 of about 282,607 (316)

Flamingo Regulates R8 Axon-Axon and Axon-Target Interactions in the Drosophila Visual System [PDF]

Current Biology, 2003
Photoreceptors (R cells) in the Drosophila retina connect to targets in three distinct layers of the optic lobe of the brain: R1-R6 connect to the lamina, and R7 and R8 connect to distinct layers in the medulla. In each of these layers, R axon termini are arranged in evenly spaced topographic arrays. In a genetic screen for mutants with abnormal R cell
Senti, K A, Usui, T, Boucke, K, Greber, U F, Uemura, T, Dickson, B J   +5 more
openaire   +5 more sources

Decreto ateniese relativo alla concessione della sitesis

Axon, 2023
Il decreto ateniese qui discusso presenta alcuni aspetti problematici, tra cui la datazione, che oscilla tra il 440 e il 424 a.C. e lo stesso contenuto del documento.
Tentori Montalto, Marco, Cardinale, Sandy, Pizzoli, Lorenzo   +2 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Addressing climate change at the community level: opportunities for, and challenges to, mainstreaming sustainable development [PDF]

In recent years, the UK has positioned itself to become a global leader in addressing climate change. Alongside this positioning, there has been an increasing emphasis on the role of communities to facilitate and sustain carbon reduction practices ...
Axon, Stephen
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Neuronal Dynamics and Axonal Flow: Axonal Peristalsis [PDF]

Proceedings of the National Academy of Sciences, 1972
By time-lapse, phase-contrast cinemicrography of sensory nerve fibers of young mice, isolated with their originating spinal ganglia in nutrient solution, the postulated peristaltic surface drive of the cellulifugal propulsion of the semisolid axonal column at a rate of the order of 1 mm/day (1 μm/min) could be verified and quantitatively analyzed.
openaire   +2 more sources

microRNAs in axon guidance [PDF]

Frontiers in Cellular Neuroscience, 2014
Brain wiring is a highly intricate process in which trillions of neuronal connections are established. Its initial phase is particularly crucial in establishing the general framework of neuronal circuits. During this early step, differentiating neurons extend axons, which reach their target by navigating through a complex environment with extreme ...
Iyer, A. N., Bellon, A., Baudet, M. L.
openaire   +3 more sources

La tablette de bronze d’Idalion

Axon, 2021
Contrat conclu entre le roi et la cité d’Idalion, d’une part, et le médecin Onasilos et ses frères, de l’autre part, au sujet de la récompense de ceux-ci pour avoir soigné les blessés pendant le siège de la ville par les Mèdes et les Kitiens.
Perdicoyianni-Paleologou, Helen
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source