Results 101 to 110 of about 6,093,797 (222)
Frontiers in Neuroanatomy, 2014 Here we review recent findings related to postnatal spinogenesis, dendritic and axon growth, pruning and electrophysiology of neocortical pyramidal cells in the developing primate brain.
G. Elston, I. Fujita
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PLoS GeneticsThe pathway for axon regeneration in Caenorhabditis elegans is activated by SVH-1, a growth factor belonging to the HGF/plasminogen family. SVH-1 is a dual-function factor that acts as an HGF-like growth factor to promote axon regeneration and as a ...
Tatsuhiro Shimizu +3 more
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Regulation of intrinsic axon growth ability at retinal ganglion cell growth cones.
Investigative Ophthalmology and Visual Science, 2014 PURPOSE Mammalian central nervous system neurons fail to regenerate after injury or disease, in part due to a progressive loss in intrinsic axon growth ability after birth. Whether lost axon growth ability is due to limited growth resources or to changes
M. Steketee +8 more
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A neural network growing algorithm based on Brownian movement and gravity constraint
Advances in Mechanical Engineering, 2018 A growing algorithm of neural network based on axon growth is developed in this article. At the beginning, the Newtonian gravitation and the Brownian motion are employed to establish an axon growth model, and the constraint function of the neural axon ...
Ming Liu +5 more
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Motor neuron synapse and axon defects in a C. elegans alpha-tubulin mutant.
PLoS ONE, 2010 Regulation of microtubule dynamics underlies many fundamental cellular mechanisms including cell division, cell motility, and transport. In neurons, microtubules play key roles in cell migration, axon outgrowth, control of axon and synapse growth, and ...
Renee Baran +5 more
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SRF Phosphorylation by Glycogen Synthase Kinase-3 Promotes Axon Growth in Hippocampal Neurons
Journal of Neuroscience, 2014 The growth of axons is an intricately regulated process involving intracellular signaling cascades and gene transcription. We had previously shown that the stimulus-dependent transcription factor, serum response factor (SRF), plays a critical role in ...
Cong L Li +4 more
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Promotion of Axon Growth by the Secreted End of a Transcription Factor
Cell Reports, 2019 Summary: Axon growth is regulated externally by attractive and repulsive cues generated in the environment. In addition, intrinsic pathways govern axon development, although the extent to which axons themselves can influence their own growth is unknown ...
Ethan P. McCurdy +3 more
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Interleukin-4 protects retinal ganglion cells and promotes axon regeneration
Cell Communication and SignalingBackground The preservation of retinal ganglion cells (RGCs) and the facilitation of axon regeneration are crucial considerations in the management of various vision-threatening disorders. Therefore, we investigate the efficacy of interleukin-4 (IL-4), a
Zhaoyang Zuo +5 more
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Regulation of retinal axon growth by secreted Vax1 homeodomain protein
eLife, 2014 Retinal ganglion cell (RGC) axons of binocular animals cross the midline at the optic chiasm (OC) to grow toward their synaptic targets in the contralateral brain. Ventral anterior homeobox 1 (Vax1) plays an essential role in the development of the OC by
Namsuk Kim +9 more
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Biomedicines, 2020 NeurotrophiŃ factors play a key role in the development, differentiation, and survival of neurons and nerve regeneration. In the present study, we evaluated the effect of certain neurotrophic factors (NGF, BDNF, and GDNF) on axon growth and migration of ...
Polina Klimovich +3 more
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