Results 51 to 60 of about 6,316,330 (345)
MiR-124 Promotes the Growth of Retinal Ganglion Cells Derived from Müller Cells
Cellular Physiology and Biochemistry, 2018 Background/Aims: Retinal Müller cells could be induced to differentiate into retinal ganglion cells (RGCs), but RGCs derived from Müller cells have defects in axon growth, leading to a defect in signal conduction.
Ye He +5 more
doaj +1 more source
The Krüppel-Like Factor Gene Target Dusp14 Regulates Axon Growth and Regeneration
Investigative Ophthalmology and Visual Science, 2018 Purpose Adult central nervous system (CNS) neurons are unable to regenerate their axons after injury. Krüppel-like transcription factor (KLF) family members regulate intrinsic axon growth ability in vitro and in vivo, but mechanisms downstream of these ...
J. Galvao +9 more
semanticscholar +1 more source
Chemokines induce axon outgrowth downstream of Hepatocyte Growth Factor and TCF/β-catenin signaling
Frontiers in Cellular Neuroscience, 2013 Axon morphogenesis is a complex process regulated by a variety of secreted molecules, including morphogens and growth factors, resulting in the establishment of the neuronal circuitry. Our previous work demonstrated that growth factors (Neurotrophins (NT)
Deepshikha eBhardwaj +7 more
doaj +1 more source
Axonal Neuropathy-associated TRPV4 Regulates Neurotrophic Factor-derived Axonal Growth [PDF]
Journal of Biological Chemistry, 2012 Spinal muscular atrophy and hereditary motor and sensory neuropathies are characterized by muscle weakness and atrophy caused by the degenerations of peripheral motor and sensory nerves. Recent advances in genetics have resulted in the identification of missense mutations in TRPV4 in patients with these hereditary neuropathies. Neurodegeneration caused
Yongwoo, Jang +12 more
openaire +2 more sources
Journal of Neuroscience, 2017 During embryonic development, axons extend over long distances to establish functional connections. In contrast, axon regeneration in the adult mammalian CNS is limited in part by a reduced intrinsic capacity for axon growth.
Eljo Y. van Battum +13 more
semanticscholar +1 more source
The Virtuous Cycle of Axon Growth: Axonal Transport of Growth‐Promoting Machinery as an Intrinsic Determinant of Axon Regeneration [PDF]
Developmental Neurobiology, 2018 ABSTRACTInjury to the brain and spinal cord has devastating consequences because adult central nervous system (CNS) axons fail to regenerate. Injury to the peripheral nervous system (PNS) has a better prognosis, because adult PNS neurons support robust axon regeneration over long distances.
Petrova, Veselina, Eva, R
openaire +3 more sources
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Non-Muscle Myosin II in Axonal Cell Biology: From the Growth Cone to the Axon Initial Segment
Cells, 2020 By binding to actin filaments, non-muscle myosin II (NMII) generates actomyosin networks that hold unique contractile properties. Their dynamic nature is essential for neuronal biology including the establishment of polarity, growth cone formation and ...
Ana Rita Costa, Monica M. Sousa
doaj +1 more source
The Dyslexia-susceptibility Protein KIAA0319 Inhibits Axon Growth Through Smad2 Signaling
Cerebral Cortex, 2017 KIAA0319 is a transmembrane protein associated with dyslexia with a presumed role in neuronal migration. Here we show that KIAA0319 expression is not restricted to the brain but also occurs in sensory and spinal cord neurons, increasing from early ...
F. Franquinho +9 more
semanticscholar +1 more source