Results 301 to 310 of about 104,244 (349)
Anatomical Progression of Neuropathology in FTLD‐TDP Type C and Linkage to Annexin A11
Annals of Neurology, EarlyView.Objective Frontotemporal lobar degenerations (FTLD)‐TDP type C (TDP‐C) is distinguished from other FTLD‐TDP subtypes by 3 unique features: (1) invariable onset in the anterior temporal lobe (ATL), (2) phosphorylated TDP‐43 (pTDP) neurites in cortex, and (3) colocalization of all pTDP deposits with annexin A11 (ANXA11).
Allegra Kawles +7 more
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Bioprinted Excitable Tissues with Multistimulation Systems for Promoting Function and Maturation
Advanced NanoBiomed Research, EarlyView.This review provides an overview of stimulation strategies used to enhance the functional maturation of bioprinted excitable tissues. It addresses key limitations in physiological performance of bioprinted excitable tissues, outlines major stimulation modalities—including electrical, mechanical, optical, magnetic, ultrasound, and hybrid—and examines ...
Uijung Yong, Jinseon Park, Jinah Jang
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.Engineered biomaterial interfaces critically control retinal organoid development. This study examines how surface modifications (amine, hydroxyl, phenyl, and methyl groups) dictate organoid response. Hydrophilic surfaces markedly increase migration and foster retinal ganglion cell differentiation.
Luis Marcos +4 more
wiley +1 more source
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Cell and Tissue Research, 1997
The segmental arrangement of spinal nerves in higher vertebrate embryos provides a simple system in which to study the factors that influence axon pathfinding. Developing motor and sensory axons are intimately associated with surrounding tissues that direct axon guidance. We argue that two distinct guidance mechanisms, viz.
, Tannahill, , Cook, , Keynes
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The segmental arrangement of spinal nerves in higher vertebrate embryos provides a simple system in which to study the factors that influence axon pathfinding. Developing motor and sensory axons are intimately associated with surrounding tissues that direct axon guidance. We argue that two distinct guidance mechanisms, viz.
, Tannahill, , Cook, , Keynes
openaire +3 more sources
Current Opinion in Neurobiology, 2006
Our knowledge about molecular mechanisms underlying axon guidance along the antero-posterior axis in contrast to the dorso-ventral axis of the developing nervous system is very limited. During the past two years in vitro and in vivo studies have indicated that morphogens have a role in longitudinal axon guidance.
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Our knowledge about molecular mechanisms underlying axon guidance along the antero-posterior axis in contrast to the dorso-ventral axis of the developing nervous system is very limited. During the past two years in vitro and in vivo studies have indicated that morphogens have a role in longitudinal axon guidance.
openaire +3 more sources
European Journal of Neuroscience, 1997
AbstractAxon guidance by target‐derived diffusible factors plays an important role in the development of the nervous system. This paper considers the constraints imposed on this process by the mathematics of diffusion. A point source continuously producing a factor into an infinite three‐dimensional volume is considered as a model for both the in vivo ...
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AbstractAxon guidance by target‐derived diffusible factors plays an important role in the development of the nervous system. This paper considers the constraints imposed on this process by the mathematics of diffusion. A point source continuously producing a factor into an infinite three‐dimensional volume is considered as a model for both the in vivo ...
openaire +3 more sources
Calcium signaling in axon guidance
Trends in Neurosciences, 2014Guidance of axons to their targets in the developing nervous system requires a myriad of downstream signaling molecules to coordinate growth cone movement. One of the most important of these is calcium, and over the past few years many new insights have been gained into the role of calcium in axon guidance.
Sutherland, Daniel J. +2 more
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Axon guidance: the cytoplasmic tail
Current Opinion in Cell Biology, 2002Recent advances in the study of axon guidance have begun to clarify the intricate signalling mechanisms utilised by receptors that mediate path-finding. Many of these axon guidance receptors, including Plexin B, EphA, ephrin B and Robo, regulate the Rho family of GTPases, to effect changes in motility. Recent studies demonstrate a critical role for the
Bharatkumar N, Patel +1 more
openaire +2 more sources