Results 311 to 320 of about 104,244 (349)
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Axonal guidance in the chicken retina
Development, 1995ABSTRACT During retina development, ganglion cells extend their axons exclusively into the innermost tissue layer, but not into outer retina layers. In order to elucidate guiding mechanisms for axons, tissue strips of embryonic chicken retinae were explanted onto retinal cryosections (cryoculture).
H, Stier, B, Schlosshauer
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Repellent cues in axon guidance
Current Opinion in Neurobiology, 1992There is increasing evidence that axons are guided by repulsion in several regions of the developing nervous system, although this has yet to be confirmed directly in vivo. As more candidate repulsion molecules are identified, it is becoming clear that collapse of the growth cone in vitro may be mediated by more than one intracellular mechanism.
R J, Keynes, G M, Cook
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The Molecular Biology of Axon Guidance
Science, 1996Neuronal growth cones navigate over long distances along specific pathways to find their correct targets. The mechanisms and molecules that direct this pathfinding are the topics of this review. Growth cones appear to be guided by at least four different mechanisms: contact attraction, chemoattraction, contact repulsion, and chemorepulsion. Evidence is
M, Tessier-Lavigne, C S, Goodman
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Wnt signaling in axon guidance
Trends in Neurosciences, 2004Recent studies have identified Wnt proteins as conserved axon guidance molecules in vertebrates and invertebrates. Wnt proteins are a large family of diffusible factors that play several important roles, both in embryonic development and in adult function.
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Axon Guidance in the Dopamine System
2009Meso-diencephalic dopamine neurons (mdDA) neurons are located in the retrorubral field (RRF), substantia nigra pars compacta (SNc) and ventral tegmental area (VTA) and give rise to prominent ascending axon projections. These so-called mesotelencephalic projections are organized into three main pathways: the mesostriatal, mesocortical and mesolimbic ...
Asheeta A, Prasad, R Jeroen, Pasterkamp
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Ephrin signaling in axon guidance
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2004The multiple functions of a neuron depend on the proper assembly of axonal connections during the development of the nervous systems. This assembly involves the motile behavior of growth cones at the ends of elongating axons. The growth cones express receptors that bind to specific guidance molecules in the local environment.
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Axon guidance by molecular gradients
Current Opinion in Neurobiology, 1992In the past year, evidence indicating that some developing axons are guided to their targets, at least in part, by gradients of diffusible chemoattractants secreted by their target cells has continued to accumulate. It has also been shown for the first time that axons can orient in response to smooth gradients of immobilized substrate molecules.
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