Results 91 to 100 of about 57,333 (280)
Advanced Functional Materials, EarlyView.Controlled laser‐drilling of embedded HfO2 membranes creates three layer nanopores with Gaussian‐shaped cavities sculptured in the supporting layers. These embedded solid‐state nanopores slow DNA translocation by 12‐fold compared to SiNx pores, enabling high‐resolution, label‐free detection of short DNAs, RNAs, and proteins.
Jostine Joby +4 more
wiley +1 more source
FGF14 localization and organization of the axon initial segment [PDF]
Molecular and Cellular Neuroscience, 2013 The axon initial segment (AIS) is highly enriched in the structural proteins ankyrin G and βIV-spectrin, the pore-forming (α) subunits of voltage-gated sodium (Nav) channels, and functional Nav channels, and is critical for the initiation of action potentials.
Maolei, Xiao +3 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.A W/NbOx/Pt memristor demonstrates the coexistence of volatile, non‐volatile, and threshold switching characteristics. Volatile switching serves as a reservoir computing layer, providing dynamic short‐term processing. Non‐volatile switching, stabilized through ISPVA, improves reliable long‐term readout. Threshold switching operates as a leaky integrate
Ungbin Byun, Hyesung Na, Sungjun Kim
wiley +1 more source
Periadolescent Maturation of GABAergic Hyperpolarization at the Axon Initial Segment
Cell Reports, 2017 Neuronal chloride levels are developmentally regulated. Early in life, high intracellular concentrations support chloride efflux and depolarization at GABAergic synapses.
Gina Rinetti-Vargas +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A van der Waals optoelectronic synaptic device based on a ReS2/WSe2 heterostructure and oxygen‐treated h‐BN is presented, which enables both positive and negative PSCs through photocarrier polarity reversal. Bidirectional plasticity arises from gate‐tunable band bending and charge trapping‐induced quasi‐doping.
Hyejin Yoon +9 more
wiley +1 more source
Hippocampal Chandelier Cells Modulate Seizure Susceptibility and Severity
Advanced ScienceThe axon initial segment (AIS), serving as the site for initiating action potentials (APs), is a key target for efficient regulation of neuronal activity.
Yang Li +7 more
doaj +1 more source
The avian tectobulbar tract: development, explant culture, and effects of antibodies on the pattern of neurite outgrowth [PDF]
, 1990 The tectobulbar tract is the first long-distance projecting fiber pathway to appear during the development of the avian optic tectum (dorsal half of the mesencephalon).
Kröger, Stephan, Schwarz, U.
core +2 more sources
IκBα is not required for axon initial segment assembly [PDF]
Molecular and Cellular Neuroscience, 2012 The inhibitor of NF-κB alpha (IκBα) protein is an important regulator of the transcription factor NF-κB. In neurons, IκBα has been shown to play a role in neurite outgrowth and cell survival. Recently, a phosphorylated form of IκBα (pIκBα Ser32/36) was reported to be highly enriched at the axon initial segment (AIS) and was proposed to function ...
Shelly A, Buffington +3 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta +4 more
wiley +1 more source
The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier. [PDF]
, 2019 TRAAK is a membrane tension-activated K+ channel that has been associated through behavioral studies to mechanical nociception. We used specific monoclonal antibodies in mice to show that TRAAK is localized exclusively to nodes of Ranvier, the action ...
Brohawn, Stephen +5 more
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