Results 171 to 180 of about 56,490 (282)

The axon initial segment-associated microglia regulate neuronal activity and visual perception. [PDF]

Cell Res
Wang Y, Wang Q, Gao C, He S, Wei C, Song J, Liu X, Liu X, Feng S, Yao W, Wu W, Gao TM, Ren S.   +12 more
europepmc   +1 more source

Aberrant axon initial segment plasticity and intrinsic excitability of ALS hiPSC motor neurons. [PDF]

Cell Rep, 2023
Harley P, Kerins C, Gatt A, Neves G, Riccio F, Machado CB, Cheesbrough A, R'Bibo L, Burrone J, Lieberam I.   +9 more
europepmc   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

A distinct PP2A subunit regulates local protein phosphorylation at the axon initial segment. [PDF]

Nat Commun
Anderson AP, Kim S, Melton AJ, Ding X, Zhang W, Saltzman AB, Malovannaya A, Rasband MN, Gao Y.   +8 more
europepmc   +1 more source

Axon Initial Segment GABA Inhibits Action Potential Generation throughout Periadolescent Development. [PDF]

J Neurosci, 2023
Lipkin AM, Bender KJ.
europepmc   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Evaluating TRIM46's Role in Axon Initial Segment Formation. [PDF]

J Neurosci
Belmonte S.
europepmc   +1 more source

Amyloid Precursor Protein Can Cause Changes in Neuronal Firing Rates via Axon Initial Segment. [PDF]

J Neurosci, 2023
Acharyya D, Norman V.
europepmc   +1 more source

Sentience in cephalopod molluscs: an updated assessment

Biological Reviews, EarlyView.
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell, Heather Browning, Andrew Crump, Charlotte C. Burn, Jonathan Birch   +4 more
wiley   +1 more source

Absence of the axon initial segment in sensory neuron enhances resistance to amyotrophic lateral sclerosis. [PDF]

Brain
Tra NT, Kiryu-Seo S, Kida H, Wakatsuki K, Tashiro Y, Tsutsumi M, Ataka M, Iguchi Y, Nemoto T, Takahashi R, Katsuno M, Kiyama H.   +11 more
europepmc   +1 more source