Results 181 to 190 of about 28,691 (244)

Investigation on constitutive IKK activity in the axon initial segment

BMC Neuroscience, 2007
König Hans-Georg, Deller Thomas, Schultz Christian, Schwamborn Robert, Prehn Jochen   +4 more
doaj   +1 more source

Impaired axon initial segment structure and function in a model of <i>ARHGEF9</i> developmental and epileptic encephalopathy. [PDF]

Proc Natl Acad Sci U S A
Wang W, Williams DJ, Teoh JJ, Soundararajan D, Zuberi A, Lutz CM, Frankel WN, Makinson CD.   +7 more
europepmc   +1 more source

Bridging computational and clinical strategies for presurgical identification of epileptogenic networks

Epilepsia Open, EarlyView.
Abstract Objective About one third of epilepsy patients are drug‐resistant. Resective epilepsy surgery remains a key treatment option but depends critically on accurate identification of the seizure onset zone (SOZ), which is still guided mainly by subjective visual inspection of electrophysiological signals.
Tena Dubcek, Debora Ledergerber, Kristina Koenig, Adham Elshahabi, Rafael Polania, Lukas Imbach   +5 more
wiley   +1 more source

Altered gene expression in the liver and small intestine of horses with equine neuroaxonal dystrophy

Equine Veterinary Journal, EarlyView.
Abstract Background Equine neuroaxonal dystrophy/degenerative myeloencephalopathy (eNAD/EDM) is the second most common diagnosis of spinal ataxia in horses in the United States. The disease develops due to a combination of vitamin E deficiency and an unknown genetic risk factor(s), and there currently is no effective treatment.
Stephanie Ryan, Blythe Durbin‐Johnson, Kevin Woolard, Andrew D. Miller, Carrie J. Finno   +4 more
wiley   +1 more source

A Human Touch: Hominid-Specific LRRC37B Regulates Axon Initial Segment Excitability. [PDF]

Epilepsy Curr
Dabrowski AK, Goldberg EM.
europepmc   +1 more source

Quadruplex Bioactive FAND for Treating Acute Liver Failure Induced by Acetaminophen or Hepatectomy

Exploration, EarlyView.
This work developed a bioactive quadruplex FANDHP@FuEVs with intrinsic inflammation‐targeting properties of M2‐EVs and MSC‐EVs, harnessing the synergistic biological activities by leveraging four natural active components—M2‐EVs, MSC‐EVs, HGF, and PPC—to deliver pleiotropic therapies, including antioxidant, anti‐inflammatory, pro‐regenerative, and M1 ...
Meng Sun, Fang Fang, Juan Liu, Yueyun Fan, Sa Wang, Chuang Zhang, Weiyu Li, Zhengyang Quan, Dongxu Zhao, Min Hu, Jinfeng Zhang   +10 more
wiley   +1 more source

The TRPM2–PARP‐1 Axis Involvement in Bisphenol A and Nonylphenol‐Induced Ferroptosis in Trigeminal Ganglion Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental contaminants like bisphenol A (BPA) and nonylphenol (NP) are recognized neurotoxicants; however, the molecular mechanisms underlying their impact on sensory ganglia, specifically the trigeminal ganglion (TG), remain critically underexplored.
Betül Yazğan, Musa Tatar, Yener Yazğan, Kıymet Kübra Tüfekci   +3 more
wiley   +1 more source

Editorial: Axon neurobiology: updates in functional and structural dynamics

Frontiers in Cellular Neuroscience
Haruyuki Kamiya, Dominique Debanne
doaj   +1 more source

Transcriptomic alterations in APP/PS1 mice astrocytes lead to early postnatal axon initial segment structural changes. [PDF]

Cell Mol Life Sci
Benitez MJ, Retana D, Ordoñez-Gutiérrez L, Colmena I, Goméz MJ, Álvarez R, Ciorraga M, Dopazo A, Wandosell F, Garrido JJ.   +9 more
europepmc   +1 more source

Partitioned Internal Auditory Canal: Association With Cochlear Aperture Anomalies

The Laryngoscope, EarlyView.
Partitioned internal auditory canal (IAC), defined by a bony septum separating the facial nerve from the cochleovestibular nerve, occurs significantly more often in ears with stenotic or atretic cochlear aperture. ABSTRACT Objective To investigate the association between partitioned internal auditory canal (IAC) and other inner ear abnormalities ...
Levent Sennaroğlu, Emel Tahir
wiley   +1 more source