Results 201 to 210 of about 28,691 (244)

Amyloid-β-induced disruption of axon-initial-segment mitochondria localization: consequences for TAU missorting in Alzheimer's disease pathology. [PDF]

Neural Regen Res
Adam D, Langerscheidt F, Zempel H.
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

A Realistic In Silico Brain Phantom for Quantifying Susceptibility Anisotropy‐Induced Error in Susceptibility Separation

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To create a realistic in silico brain phantom for positive and negative magnetic susceptibility that incorporates susceptibility anisotropy, enabling the evaluation of how susceptibility anisotropy influences susceptibility separation algorithm performance.
Daniel Ridani, Benjamin De Leener, Eva Alonso‐Ortiz   +2 more
wiley   +1 more source

Analysis of the effect of the scorpion toxin AaH-II on action potential generation in the axon initial segment. [PDF]

Sci Rep
Abbas F, Blömer LA, Millet H, Montnach J, De Waard M, Canepari M.   +5 more
europepmc   +1 more source

Dependence of the Extra‐Cellular Diffusion Coefficient on the Fractions of Neurites and Cell Bodies in Gray Matter

Magnetic Resonance in Medicine, EarlyView.
Purpose The dependence of the long‐time (tortuosity) limit of the extra‐cellular diffusivity on the intra‐cellular volume fraction is of fundamental importance for microstructure modeling. While such dependencies have been explored for the white matter, the tortuosity limit in gray matter is unknown due to complex cell composition and geometry. Here we
Hong‐Hsi Lee, Ali Abdollahzadeh, Hansol Lee, Ricardo Coronado‐Leija, Els Fieremans, Susie Y. Huang, Dmitry S. Novikov   +6 more
wiley   +1 more source

Static magnetic stimulation induces structural plasticity at the axon initial segment of inhibitory cortical neurons. [PDF]

Sci Rep
Beros JL, King ES, Clarke D, Jaeschke-Angi L, Rodger J, Tang AD.   +5 more
europepmc   +1 more source

A Deep Nonlinear Subspace Modeling and Reconstruction for Diffusion‐Weighted Imaging Using Denoising Auto‐Encoder

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To present a novel, nonlinear subspace modeling and joint k–q‐space reconstruction technique for high‐resolution, multi‐band, multi‐shell diffusion‐weighted imaging (DWI). Methods High b‐value (> 1000 s/mm2), high resolution DWI has the drawback of generally low signal‐to‐noise ratios (SNRs).
Julius Glaser, Zhengguo Tan, Annika Hofmann, Frederik Bernd Laun, Florian Knoll   +4 more
wiley   +1 more source

Comparative Systematic Analysis of Gray Matter Biophysical Models on a Public Dataset

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Biophysical models of diffusion tailored to characterize gray matter (GM) microstructure are gaining traction in the neuroimaging community. NEXI, SMEX, SANDI, and SANDIX represent recent efforts to account for different microstructural features, such as soma contributions and inter‐compartment exchange, in the diffusion MRI (dMRI ...
Santiago Mezzano, Quentin Uhl, Tommaso Pavan, Jasmine Nguyen‐Duc, Hansol Lee, Susie Huang, Ileana Jelescu   +6 more
wiley   +1 more source

Electrical Modalities in the Rehabilitation of Peripheral Nerve Injuries: State of the Literature and Current Clinical Applications

Muscle &Nerve, EarlyView.
ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith, Kirsten M. Schlosser, Ranee Munaim, Stephanie H. Vu, JulieAnn H. Uh, Yusha K. Liu   +5 more
wiley   +1 more source

Targeted Muscle Reinnervation for Intuitive Prosthetic Control

Muscle &Nerve, EarlyView.
ABSTRACT The convergence of medical and technological advances has led to a substantial expansion of therapeutic approaches for patients with limb amputations. Targeted muscle reinnervation (TMR) is one of the strategies to improve control of bionic arms and has been applied for more than two decades. Through surgical rewiring of the nerves responsible
Nitay Maile, Laura Ferrante, Dario Farina, Ulla Al Dabbass, Oskar C. Aszmann, Vlad Tereshenko   +5 more
wiley   +1 more source