Results 241 to 250 of about 57,333 (280)

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

open access: yesIbrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Gradual volatile memristor–based artificial neurons with high uniformity for neuromorphic computing

open access: yesInfoScience, EarlyView.
Schematic of leaky integrate‐and‐fire artificial neurons for MNIST image classification. Abstract Artificial neurons are pivotal for neuromorphic hardware, but the development of compact and uniform devices remains challenging. Conventional volatile memristors suffer from abrupt switching, which hinders spatiotemporal consistency.
Pengtao Li   +12 more
wiley   +1 more source

Organic neuromorphic electronics powering intelligent sensory and edge computing systems

open access: yesInfoMat, EarlyView.
Organic electronic materials are promising candidates for neuromorphic sensing applications, including chemical, physical, visual, and multimodal sensing, owing to their mechanical softness, biocompatibility, and intrinsic ionic–electronic coupling.
Seungjun Woo   +5 more
wiley   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

open access: yesiNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen   +6 more
wiley   +1 more source

Synchronous Regeneration: Key Mechanism for Selective Reinnervation in Bilateral Vocal Fold Paralysis

open access: yesThe Laryngoscope, EarlyView.
This study investigates the mechanisms behind the success of selective laryngeal reinnervation surgery in bilateral vocal fold paralysis. In an animal model, the surgery promoted neuromuscular regeneration and restored coordinated vocal fold movement, with no misdirected potentials observed.
Meng Li   +7 more
wiley   +1 more source

Placental‐Derived Connective Tissue Matrix Mediates Murine Recurrent Laryngeal Nerve Regeneration

open access: yesThe Laryngoscope, EarlyView.
Placentally derived connective tissue matrix (pd‐CTM) innately contains various neurotrophic, angiogenic, anti‐inflammatory, and tissue remodeling cytokines. In this mouse model of unilateral vocal fold paralysis, we investigate its effects on recurrent laryngeal nerve (RLN) regeneration and reinnervation of the right thyroarytenoid (TA) muscle after ...
Sunjay Anekal   +7 more
wiley   +1 more source
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Axonal injury alters the extracellular glial environment of the axon initial segment and allows substantial mitochondrial influx into axon initial segment

Journal of Comparative Neurology, 2021
Abstract The axon initial segment (AIS) is structurally and functionally distinct from other regions of the axon, yet alterations in the milieu of the AIS after brain injury have not been well characterized. In this study, we have examined extracellular and intracellular changes in the AIS after hypoglossal nerve ...
Hiromi Tamada   +3 more
openaire   +2 more sources

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