Results 91 to 100 of about 174,919 (258)

Recent Advances in the Molecular and Cellular Mechanisms of gp120-Mediated Neurotoxicity

open access: yesCells, 2022
Axonal degeneration and loss of synapses are often seen in different brain areas of people living with human immunodeficiency virus (HIV). Nevertheless, the underlying causes of the pathological alterations observed in these individuals are poorly ...
Valeria Avdoshina, Italo Mocchetti
doaj   +1 more source

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

open access: yesAdvanced Science, EarlyView.
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng   +8 more
wiley   +1 more source

Genome survey sequence of black carp provides insights into development‐related gene duplications

open access: yesJournal of the World Aquaculture Society, Volume 53, Issue 6, Page 1197-1214, December 2022., 2022
Abstract As one of the traditional "Four Domesticated Fishes" in China, black carp (Mylopharyngodon piceus) is an important species in freshwater aquaculture, an important fishery resource in China, and an invasive species in the United Sates. Here, we reported the draft genome of black carp with an estimated size of 975 Mb and 27,541 predicted protein‐
Ying Lu   +10 more
wiley   +1 more source

Cerebellar axonopathy in Shivers horses identified by spatial transcriptomic and proteomic analyses

open access: yesJournal of Veterinary Internal Medicine, 2023
Background Shivers in horses is characterized by abnormal hindlimb movement when walking backward and is proposed to be caused by a Purkinje cell (PC) axonopathy based on histopathology.
Stephanie J. Valberg   +3 more
doaj   +1 more source

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

open access: yesAdvanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

Actin Cytoskeleton Affects Schwann Cell Migration and Peripheral Nerve Regeneration

open access: yesFrontiers in Physiology, 2018
Actin cytoskeleton regulates many essential biological functions, including cellular development, shape, polarity, and motility. The organization of actin cytoskeleton has also been associated with numerous physiological and pathological conditions, for ...
Yaxian Wang   +3 more
doaj   +1 more source

A Fractional Viscoelastic Model Of The Axon In Brain White Matter [PDF]

open access: yesarXiv, 2023
Traumatic axonal injury occurs when loads experienced on the tissue-scale are transferred to the individual axons. Mechanical characterization of axon deformation especially under dynamic loads however is extremely difficult owing to their viscoelastic properties.
arxiv  

Graphene promotes axon elongation through local stall of Nerve Growth Factor signaling endosomes [PDF]

open access: yes, 2020
Several works reported increased differentiation of neuronal cells grown on graphene; however, the molecular mechanism driving axon elongation on this material has remained elusive. Here, we study the axonal transport of nerve growth factor (NGF), the neurotrophin supporting development of peripheral neurons, as a key player in the time course of ...
arxiv   +1 more source

Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT

open access: yesAdvanced Science, EarlyView.
Schematic diagram illustrating the mechanism of shortened lifespan in Thy 1‐C/EBPβ transgenic mice and intervention strategies. Briefly, C/EBPβ/AEP escalation in the aging brain triggers NAMPT fragmentation and NAD+ depletion. Knockout of AEP from Thy 1‐C/EBPβ Tg/Tg mice ameliorates cognitive impairments and elongates the lifespan.
Bowei Li   +8 more
wiley   +1 more source

Axonal plasticity in response to active forces generated through magnetic nano-pulling

open access: yesCell Reports, 2023
Summary: Mechanical force is crucial in guiding axon outgrowth before and after synapse formation. This process is referred to as “stretch growth.” However, how neurons transduce mechanical input into signaling pathways remains poorly understood. Another
Alessandro Falconieri   +12 more
doaj  

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