Results 101 to 110 of about 174,919 (258)
Advanced Science, EarlyView.Here a transcranial photo‐biomodulation approach is developed using near‐infrared (NIR) laser on hippocampus of mice, revealing significant improvements in learning and memory ability of mice under normal and disease conditions. The improvement results from the high‐density cell‐induced NIR local energy deposition, neuronal activation, and axonogenesis
Wei‐Tong Pan +6 more
wiley +1 more source
Assembly and turnover of neurofilaments in growing axonal neurites
Biology Open, 2018 Neurofilaments (NFs) are thought to provide stability to the axon. We examined NF dynamics within axonal neurites of NB2a/d1 neuroblastoma by transient transfection with green fluorescent protein-tagged NF-heavy (GFP-H) under the control of a ...
Edward F. Boumil +4 more
doaj +1 more source
gACSON software for automated segmentation and morphology analyses of myelinated axons in 3D electron microscopy [PDF]
arXiv, 2021 Background and Objective: Advances in electron microscopy (EM) now allow three-dimensional (3D) imaging of hundreds of micrometers of tissue with nanometer-scale resolution, providing new opportunities to study the ultrastructure of the brain. In this work, we introduce a freely available Matlab-based gACSON software for visualization, segmentation ...
arxiv
Notch signalling in adult neurons: a potential target for microtubule stabilization
Therapeutic Advances in Neurological Disorders, 2013 Cytoskeletal dysfunction has been proposed during the last decade as one of the main mechanisms involved in the aetiology of several neurodegenerative diseases.
Sara Anna Bonini +3 more
doaj +1 more source
Autism Research, EarlyView.ABSTRACT Among autistic individuals, a subphenotype of disproportionate megalencephaly (ASD‐DM) seen at three years of age is associated with co‐occurring intellectual disability and poorer prognoses later in life. However, many of the genes contributing to ASD‐DM have yet to be delineated. In this study, we identified additional ASD‐DM candidate genes
Sierra S. Nishizaki +10 more
wiley +1 more source
Progress of Research on Diffuse Axonal Injury after Traumatic Brain Injury
Neural Plasticity, 2016 The current work reviews the concept, pathological mechanism, and process of diagnosing of DAI. The pathological mechanism underlying DAI is complicated, including axonal breakage caused by axonal retraction balls, discontinued protein transport along ...
Junwei Ma +3 more
doaj +1 more source
Artificial intelligence‐assisted design, synthesis and analysis of smart biomaterials
BMEMat, EarlyView.Smart biomaterials are rapidly emerging as tools for tissue engineering, and artificial intelligence has played essential roles in biomaterial studies. By bridging the literature gap in AI‐based design, synthesis and analysis of smart biomaterials, the current review shares perspectives on how biomaterial scientists can practically incorporate AI for ...
Pengfei Jiang +9 more
wiley +1 more source
Anais da Academia Brasileira de Ciências, 2001 In this paper we report a qualitative morphological analysis of Wallerian degeneration in a marsupial. Right optic nerves of opossums Didelphis marsupialis were crushed with a fine forceps and after 24, 48, 72, 96 and 168 hours the animals were ...
MARCELO S. NARCISO +2 more
doaj +1 more source
Heterogeneous distribution of axonal cytoskeleton proteins in the human optic nerve.
Investigative Ophthalmology and Visual Science, 2009 PURPOSE Cytoskeleton proteins play a critical role in maintaining retinal ganglion cell structure, viability, and function. This study documents the distribution of cytoskeleton protein subunits in the various regions of the normal human optic nerve and ...
Chandrakumar Balaratnasingam +4 more
semanticscholar +1 more source
Acta Neuropathologica Communications, 2020 Protein inclusions containing the RNA-binding protein TDP-43 are a pathological hallmark of amyotrophic lateral sclerosis and other neurodegenerative disorders.
Michael Briese +9 more
doaj +1 more source