Results 111 to 120 of about 174,919 (258)
Tau protein and adult hippocampal neurogenesis
Frontiers in Neuroscience, 2012 Tau protein is a microtubule associated protein found in the axonal compartment that stabilizes neuronal microtubules under normal physiological conditions.
Almudena eFuster-Matanzo +9 more
doaj +1 more source
Cell Biology International, EarlyView.ABSTRACT Alzheimer's disease (AD) is prevalent in the elderly population and characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), composed of tau proteins, and extracellular deposition of beta‐amyloid protein (Aβ). The present study aimed to investigate the neuroprotective effects of melatonin on Aβ42‐induced AD‐like ...
Jiraporn Panmanee +11 more
wiley +1 more source
Damage to Myelin and Oligodendrocytes: A Role in Chronic Outcomes Following Traumatic Brain Injury?
Brain Sciences, 2013 There is increasing evidence in the experimental and clinical traumatic brain injury (TBI) literature that loss of central myelinated nerve fibers continues over the chronic post-traumatic phase after injury.
William L. Maxwell
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Cytoskeleton, EarlyView.ABSTRACT Cells have an intrinsic ability to rapidly respond to environmental change to regulate cell cycle progression and membrane organisation, thereby affecting cell growth and division. The actin cytoskeleton is a highly dynamic complex of proteins that can rapidly reorganise to change the growth pattern of a cell.
Holly R. Brooker +7 more
wiley +1 more source
The paranodal cytoskeleton clusters Na+ channels at nodes of Ranvier
eLife, 2017 A high density of Na+ channels at nodes of Ranvier is necessary for rapid and efficient action potential propagation in myelinated axons. Na+ channel clustering is thought to depend on two axonal cell adhesion molecules that mediate interactions between ...
Veronique Amor +8 more
doaj +1 more source
Actin Remodeling and Polymerization Forces Control Dendritic Spine Morphology [PDF]
arXiv, 2015 Dendritic spines are small membranous structures that protrude from the neuronal dendrite. Each spine contains a synaptic contact site that may connect its parent dendrite to the axons of neighboring neurons. Dendritic spines are markedly distinct in shape and size, and certain types of stimulation prompt spines to evolve, in fairly predictable fashion,
arxiv
Exploring biomarkers of neurodegeneration in epilepsy: Critical insights
Epileptic Disorders, EarlyView.Abstract The advent of biofluid biomarkers for neurodegenerative disorders has precipitated a surge in recent evidence regarding their role in epilepsy. In this literature review, we examine the diagnostic, prognostic, and therapeutic potential of several biomarkers, including amyloid‐beta (Aβ) protein, total (t‐tau), phosphorylated tau (p‐tau) protein,
Rida Farhan +7 more
wiley +1 more source
Role of calpains in the injury-induced dysfunction and degeneration of the mammalian axon
Neurobiology of Disease, 2013 Axonal injury and degeneration, whether primary or secondary, contribute to the morbidity and mortality seen in many acquired and inherited central nervous system (CNS) and peripheral nervous system (PNS) disorders, such as traumatic brain injury, spinal
Marek Ma
doaj
Ukrainian Neurosurgical Journal, 2011 The goal of study was to estimate the structural damage of axons in rats with severe traumatic brain injury (TBI), and the possibilities of such disorders correction by means of gene therapy that launches the synthesis of e3 isoform of ...
Vadym Biloshytsky +2 more
doaj +1 more source
Spectrin forms a periodic cytoskeleton within the epidermis to preserve axonal integrity [PDF]
, 2022 Sean Coakley +2 more
openalex +1 more source