Results 121 to 130 of about 174,919 (258)

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

open access: yesExploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang   +4 more
wiley   +1 more source

BDNF/trkB Induction of Calcium Transients through Cav2.2 Calcium Channels in Motoneurons Corresponds to F-actin Assembly and Growth Cone Formation on β2-Chain Laminin (221)

open access: yesFrontiers in Molecular Neuroscience, 2017
Spontaneous Ca2+ transients and actin dynamics in primary motoneurons correspond to cellular differentiation such as axon elongation and growth cone formation.
Benjamin Dombert   +6 more
doaj   +1 more source

Temporal Profiling of Male Cortical Astrocyte Transcription Predicts Molecular Shifts From Early Development to Aging

open access: yesGlia, EarlyView.
Comprehensive analysis of cortical astrocyte gene expression across the lifespan. Profiling dynamic changes of key astrocyte genes reveals functional shifts. Astrocytes contribute to gene‐length‐dependent transcription decline in the aging brain. ABSTRACT Astrocytes are the most abundant glial cell type in the central nervous system (CNS).
Xiaoran Wei   +2 more
wiley   +1 more source

Branching Law for Axons [PDF]

open access: yesarXiv, 2003
What determines the caliber of axonal branches? We pursue the hypothesis that the axonal caliber has evolved to minimize signal propagation delays, while keeping arbor volume to a minimum. We show that for a general cost function the optimal diameters of mother ($d_0$) and daughter ($d_1$, $d_2$) branches at a bifurcation obey a branching law: $d_{0}^{\
arxiv  

Nanomaterials for promoting axon regeneration after spinal cord injury: Mechanisms and prospects

open access: yesInterdisciplinary Medicine, EarlyView.
The effects of clinical therapies for spinal cord injury (SCI) are greatly limited due to poor axon regeneration. This review systematically discusses the ability of nanomaterials (NMs) to treat SCI and the mechanism underlying their therapeutic effects. The properties of NMs that are conducive to axon regeneration after SCI are outlined.
Jia Liu   +9 more
wiley   +1 more source

The role of the cytoskeleton in cell body enlargement, increased nuclear eccentricity and chromatolysis in axotomized spinal motor neurons

open access: yesBMC Neuroscience, 2005
Background When spinal motor axons are injured, the nucleolus, nucleus and cell body of the injured cell transiently increase in size, the nucleus becomes more eccentrically placed, and the organization of polyribosomes into Nissl bodies is temporarily ...
Hoke Victoria B, McIlwain David L
doaj   +1 more source

Bioelectronic Hydrogels: Exemplifying the Synergy Between Biopolymers and Conjugated Polymers

open access: yesMacromolecular Materials and Engineering, EarlyView.
This review aims to highlight the benefits of biopolymer‐based conductive hydrogels as soft bioelectronics for biointerface applications. Biopolymers deliver biocompatibility, commercial availability, low cost, and sustainability, whereas conjugated polymers provide electronic conductivity.
Thanh Nhi Tra   +2 more
wiley   +1 more source

Axonal Computations [PDF]

open access: yesarXiv, 2019
Axons functionally link the somato-dendritic compartment to synaptic terminals. Structurally and functionally diverse, they accomplish a central role in determining the delays and reliability with which neuronal ensembles communicate. By combining their active and passive biophysical properties, they ensure a plethora of physiological computations.
arxiv  

The Sorting Nexin, DSH3PX1, Connects the Axonal Guidance Receptor, Dscam, to the Actin Cytoskeleton [PDF]

open access: hybrid, 2001
Carolyn A. Worby   +5 more
openalex   +1 more source

Different parts of the mussel Gigantidas haimaensis holobiont responded differently to deep‐sea sampling stress

open access: yesIntegrative Zoology, EarlyView.
Symbiotic gill and nonsymbiotic mantle of mussel Gigantidas haimaensis responded differently to deep‐sea sampling stress caused by acute environmental changes. Sharply increased transcription factors potentially play key roles in initiating the response of sampled deep‐sea macrobenthos to the sampling stress.
Guoyong YAN   +4 more
wiley   +1 more source

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