Results 141 to 150 of about 25,196 (259)

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong   +9 more
wiley   +1 more source

JIP3 links lysosome transport to regulation of multiple components of the axonal cytoskeleton [PDF]

open access: gold, 2020
Nisha Mohd Rafiq   +4 more
openalex   +1 more source

Quantifying the Single‐Cell Morphological Landscape of Cellular Transdifferentiation through Force Field Reconstruction

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
This study reconstructs the driving force field of fibroblast‐to‐neuron transdifferentiation from sparse single‐cell images by decomposing it into flux and time‐dependent potential gradient, extending the landscape‐flux framework to non‐steady‐state systems.
Chudan Yu   +3 more
wiley   +1 more source

The formin DAAM is required for coordination of the actin and microtubule cytoskeleton in axonal growth cones [PDF]

open access: bronze, 2017
Szilárd Szikora   +10 more
openalex   +1 more source

NOX2‐Driven Oxidative Stress Promotes EndMT and Uncouples Angiogenesis–Osteogenesis at the Bone–Implant Interface in Diabetes

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
NOX2‐driven oxidative stress disrupts angiogenesis–osteogenesis coupling at the diabetic bone–implant interface. Pharmacologic inhibition and endothelial‐specific NOX2 knockout restore type‐H endothelium, suppress EndMT, and improve osseointegration.
Zimei Wu   +6 more
wiley   +1 more source

The Sorting Nexin, DSH3PX1, Connects the Axonal Guidance Receptor, Dscam, to the Actin Cytoskeleton [PDF]

open access: hybrid, 2001
Carolyn A. Worby   +5 more
openalex   +1 more source

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