The Effect of RAGE-Diaph1 Signaling Inhibition on the Progression of Peripheral Neuropathy in Diabetic Mice. [PDF]
Zglejc-Waszak K +9 more
europepmc +1 more source
Abstract Preservation of the insulin‐sensitive glomerular podocyte is imperative for normal kidney function. The protein tyrosine phosphatases (PTPs), protein tyrosine phosphatase 1B (PTP1B), T‐cell protein tyrosine phosphatase (TCPTP), and Src homology phosphatase 2 (SHP2) are established regulators of insulin signaling in vivo and implicated in renal
Grace LeBleu +6 more
wiley +1 more source
Reticulon-1 synthesis controls outgrowth and microtubule dynamics in injured cortical axons. [PDF]
Luarte A +21 more
europepmc +1 more source
Herpes simplex virus-1 utilizes the host actin cytoskeleton for its release from axonal growth cones
Kevin Danastas +5 more
openalex +1 more source
Top‐Down Proteomics Study of Aging and Sexual Dimorphism of Zebrafish Brains
ABSTRACT Aging significantly impacts brain function and increases susceptibility to neurodegenerative diseases, with notable sex dimorphism observed in aging‐related dementia, such as Alzheimer's disease. To better understand the molecular mechanisms of aging and dementia, it is essential to globally and accurately characterize biomolecules (e.g ...
Mehrdad Falamarzi Askarani +6 more
wiley +1 more source
Neuromechanobiology: Bridging Mechanobiology and Neuroscience Through Evidence and Open Questions. [PDF]
Zimkowska K +2 more
europepmc +1 more source
Wnt Signaling Pathway: Biological Function, Diseases, and Therapeutic Interventions
The Wnt signaling pathway is essential for development and tissue homeostasis, while its dysregulation drives diverse diseases. This review systematically outlines its components, functions, regulators, and preclinical models, highlighting secreted frizzled‐related proteins (SFRPs) as context‐dependent, biphasic modulators.
Xiaoyu Jin +3 more
wiley +1 more source
An epidermal membrane-associated periodic skeleton restricts endocytosis to stabilize neuron-epidermal attachment and preserve axons. [PDF]
Coakley S +3 more
europepmc +1 more source
Erratum to: Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones [PDF]
Michael Piper +6 more
openalex +1 more source
Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca +2 more
wiley +1 more source

