Results 161 to 170 of about 25,196 (259)

The Effect of RAGE-Diaph1 Signaling Inhibition on the Progression of Peripheral Neuropathy in Diabetic Mice. [PDF]

open access: yesInt J Mol Sci
Zglejc-Waszak K   +9 more
europepmc   +1 more source

Mapping of PTP1B, TCPTP, SHP2, and Putative Substrates Reveals Novel Networks in Glomerular Podocytes

open access: yesJournal of Cellular Physiology, Volume 241, Issue 1, January 2026.
Abstract Preservation of the insulin‐sensitive glomerular podocyte is imperative for normal kidney function. The protein tyrosine phosphatases (PTPs), protein tyrosine phosphatase 1B (PTP1B), T‐cell protein tyrosine phosphatase (TCPTP), and Src homology phosphatase 2 (SHP2) are established regulators of insulin signaling in vivo and implicated in renal
Grace LeBleu   +6 more
wiley   +1 more source

Reticulon-1 synthesis controls outgrowth and microtubule dynamics in injured cortical axons. [PDF]

open access: yesLife Sci Alliance
Luarte A   +21 more
europepmc   +1 more source

Herpes simplex virus-1 utilizes the host actin cytoskeleton for its release from axonal growth cones

open access: gold, 2022
Kevin Danastas   +5 more
openalex   +1 more source

Top‐Down Proteomics Study of Aging and Sexual Dimorphism of Zebrafish Brains

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 1, January 2026.
ABSTRACT Aging significantly impacts brain function and increases susceptibility to neurodegenerative diseases, with notable sex dimorphism observed in aging‐related dementia, such as Alzheimer's disease. To better understand the molecular mechanisms of aging and dementia, it is essential to globally and accurately characterize biomolecules (e.g ...
Mehrdad Falamarzi Askarani   +6 more
wiley   +1 more source

Wnt Signaling Pathway: Biological Function, Diseases, and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 1, January 2026.
The Wnt signaling pathway is essential for development and tissue homeostasis, while its dysregulation drives diverse diseases. This review systematically outlines its components, functions, regulators, and preclinical models, highlighting secreted frizzled‐related proteins (SFRPs) as context‐dependent, biphasic modulators.
Xiaoyu Jin   +3 more
wiley   +1 more source

Erratum to: Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones [PDF]

open access: gold, 2015
Michael Piper   +6 more
openalex   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 149-175, January 2026.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca   +2 more
wiley   +1 more source

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