Results 161 to 170 of about 174,919 (258)
MedComm, Volume 6, Issue 5, May 2025.Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes +4 more
wiley +1 more source
α‐Synuclein in Parkinson's Disease: From Bench to Bedside
Medicinal Research Reviews, Volume 45, Issue 3, Page 909-946, May 2025.ABSTRACT α‐Synuclein (α‐syn), a pathological hallmark of PD, is emerging as a bridging element at the crossroads between neuro/immune‐inflammatory responses and neurodegeneration in PD. Several evidence show that pathological α‐syn accumulates in neuronal and non‐neuronal cells (i.e., neurons, microglia, macrophages, skin cells, and intestinal cells ...
Gabriele Bellini +8 more
wiley +1 more source
Huntingtin regulates cytoskeleton organisation during axonal growth
, 2022 Rémi Carpentier
openalex +1 more source
Brain Pathology, Volume 35, Issue 3, May 2025.Aerobic exercise improves transfer of healthy mitochondria from astrocytes to neurons in the 5 × FAD mice. Abstract Mitochondrial dysfunction is a well‐established hallmark of Alzheimer's disease (AD). Despite recent documentation of transcellular mitochondrial transfer, its role in the pathogenesis of AD remains unclear.
Jiachen Cai +10 more
wiley +1 more source
Cytotypic differences in the protein composition of the axonally transported cytoskeleton in mammalian neurons [PDF]
, 1987 MM Oblinger +3 more
openalex +1 more source
Natural products targeting tumour angiogenesis
British Journal of Pharmacology, Volume 182, Issue 10, Page 2094-2136, May 2025.Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu +2 more
wiley +1 more source
Clinical Genetics, Volume 107, Issue 5, Page 485-494, May 2025.This systematic review identifies 137 SNPs linked to genetic disorders affecting foot morphology but finds no direct studies on common foot arch variations. The findings highlight a research gap and emphasize the need for large‐scale genetic studies to distinguish between natural variations and pathology‐driven foot deformities.
Yukun He +4 more
wiley +1 more source
JIP3 links lysosome transport to regulation of multiple components of the axonal cytoskeleton
, 2020 Nisha Mohd Rafiq +4 more
openalex +1 more source
Restoration of Cytoskeleton Homeostasis After Gigaxonin Gene Transfer for Giant Axonal Neuropathy [PDF]
, 2013 Silke Mussche +8 more
openalex +1 more source
Rac1 inhibition prevents axonal cytoskeleton dysfunction in Transthyretin Amyloid Polyneuropathy [PDF]
Joana Magalhães +14 more
openalex +1 more source