Results 171 to 180 of about 25,196 (259)

Neuronal Actin Remodeling and Its Role in Higher Nervous Activity. [PDF]

Int J Mol Sci
Zhuravlev AV.
europepmc   +1 more source

Disruption of the MAP1B-related Protein FUTSCH Leads to Changes in the Neuronal Cytoskeleton, Axonal Transport Defects, and Progressive Neurodegeneration inDrosophila [PDF]

, 2005
Alexandre Bettencourt da Cruz, Martin Schwärzel, Sabine Schulze, Mahtab Niyyati, Martin Heisenberg, Doris Kretzschmar   +5 more
openalex   +1 more source

Identification of a Novel Likely Pathogenic Variant of DIAPH3 Associated With New Phenotype of Sensorineural Hearing Loss

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
In this Chinese family with hereditary deafness, we identified a novel DIAPH3 point variant (NM_001042517.2:c.1472A>G). This variant manifests as late‐onset progressive sensorineural hearing loss, with congruent pure‐tone audiometry (PTA) and auditory brainstem response (ABR) thresholds.
Lingling Zeng, Qiuchen Zheng, Xiedong Wu, Guohui Chen, Linyi Xie, Wenxi Qiu, Fei Ning, Lan Bai, Qiujing Zhang   +8 more
wiley   +1 more source

Development of a Human Preclinical Platform for the Identification of Neuroprotective Compounds. [PDF]

Eur J Neurosci
González RG, Yilmaz EN, Albrecht S, Fucito M, Pieragostino D, Schmidt A, König S, FitzGerald U, Kuhlmann T.   +8 more
europepmc   +1 more source

Stress‐Induced Reorganization of Proteasomes Through Diffusion and Cytoskeleton‐Dependent Mechanisms

Small, Volume 22, Issue 2, 8 January 2026.
Proteotoxic stress induced by alpha‐synuclein aggregates drives rapid, cytoskeleton‐dependent re‐localization of mammalian proteasomes and formation of transient aggregate‐associated droplets (TAADs). Single‐molecule localization microscopy, light‐sheet imaging, nanopipette injection, single‐cell patch clamp, and single‐particle tracking reveal a ...
Michael J Morten, Yu Zhang, Bing Li, Jonathan X Meng, Kun Jiang, Liina Sirvio, Ji‐Eun Lee, Anna H Lippert, Matilda Burridge, Katiuska Daniela Pulgar Prieto, Alexander R Carr, Aleks Ponjavic, Steven F Lee, Daniel Finley, David Klenerman, Yu Ye   +15 more
wiley   +1 more source

Amyloid-β and Tau in Alzheimer's disease: pathogenesis, mechanisms, and interplay. [PDF]

Cell Death Dis
Abdulkhaliq AA, Kim B, Almoghrabi YM, Khan J, Ajoolabady A, Ren J, Bahijri S, Tuomilehto J, Borai A, Pratico D.   +9 more
europepmc   +1 more source

Polydopamine‐Based Antioxidant Countermeasures Against Spaceflight‐Induced Neurodegeneration

Small Science, Volume 6, Issue 1, January 2026.
Polydopamine nanoparticles (PDNPs) protect neuron‐like cells from microgravity‐ and cosmic radiation‐induced oxidative stress. Through in‐flight and ground‐based experiments, it has been shown that PDNPs preserve neuronal and mitochondrial function, markedly mitigating transcriptional dysregulation caused by spaceflight.
Alessio Carmignani, Attilio Marino, Matteo Battaglini, Melike Belenli Gümüş, Elisa Carrubba, Michele Balsamo, Giovanni Valentini, Gabriele Mascetti, Marco Vukich, Giada Graziana Genchi, Gianni Ciofani   +10 more
wiley   +1 more source

FoxO1 Responses to Chronic Oxidative Stress to Participate in Age‐Related Osteoporosis by Depriving β‐Catenin From TCF7

Aging Cell, Volume 25, Issue 1, January 2026.
Chronic oxidative stress caused by MACF1 deficiency leads to a functional switch in osteoblasts from “osteogenic differentiation” to “antioxidation.” FoxO1 responds to oxidative stress by altering the destination of β‐catenin and disrupting the balance of the FoxO1/β‐catenin–Wnt/β‐catenin pathway, thereby inhibiting osteoblast differentiation ...
Peihong Su, Xiaoli Ma, Chong Yin, Ruilin Shi, Siyu Chen, Lihuizi Yang, Meng Qu, Xinyao Jia, Qi Yu, Hui Li, Airong Qian, Ye Tian   +11 more
wiley   +1 more source

LRRK2 and the fragile synapse: a molecular prelude to Parkinson's disease? [PDF]

Biochem J
Masotti B, Tombesi G, Parisiadou L, Greggio E.   +3 more
europepmc   +1 more source

Wnt signalling and the regulation of the axonal cytoskeleton

, 2005
Monica Hoyos Flight
openalex   +1 more source