Results 181 to 190 of about 25,196 (259)

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

Cell Proliferation, Volume 59, Issue 1, January 2026.
Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng, Zuping Wu, Mengjie Wu, Liang Xie, Qianming Chen   +4 more
wiley   +1 more source

Rac1 inhibition prevents axonal cytoskeleton dysfunction in Transthyretin Amyloid Polyneuropathy [PDF]

Joana Magalhães, Vitor Rafael Oliveira Dias, Jessica Eira, Guy Novoa, Marina I. Oliveira da Silva, Hung‐Wei Kan, Andreia Dias, Eugénia Carvalho, Mariana Santos, Ana I. Seixas, Teresa Coelho, Ricardo Taipa, Joana Paes de Faria, Carolina Lemos, Márcia A. Liz, Márcia A. Liz   +15 more
openalex   +2 more sources

A role for the cholinergic neuron circadian clock in RNA metabolism and mediating neurodegeneration. [PDF]

Life Sci Alliance
Tam SB, Waldeck NJ, Wright M, Mojsilovic-Petrovic J, Baker EM, Kiskinis E, Bass J, Kalb RG.   +7 more
europepmc   +1 more source

The nanostructure of the axonal cytoskeleton and its interplay with endocytosis regulation

Wernert, Florian
openalex   +1 more source

The ER/Golgi Protein FNDC3B Facilitates Climbing Fibre to Purkinje Cell Synapse Elimination in the Developing Mouse Cerebellum

European Journal of Neuroscience, Volume 63, Issue 2, January 2026.
We investigated the role of fibronectin type III domain containing 3B (FNDC3B) in climbing fiber (CF) to Purkinje cell (PC) synapse elimination during postnatal development of the mouse cerebellum. We performed PC‐specific deletion of FNDC3B by RNAi‐mediated knockdown or PC‐specific conditional knockout in mice and examined CF to PC synapse development
Céline Louise Mercier, Takaki Watanabe, Yuto Okuno, Kyoko Matsuyama, Kyoko Kushibe, Henry Denny, Taisuke Miyazaki, Miwako Yamasaki, Meiko Kawamura, Manabu Abe, Kenji Sakimura, Masahiko Watanabe, Naofumi Uesaka, Masanobu Kano   +13 more
wiley   +1 more source

How to control synaptic autophagy from the neuronal soma. [PDF]

EMBO J
Huang S, Sigrist SJ.
europepmc   +1 more source

Principal mechanisms of extracellular matrix‐mediated cell–cell communication in physiological and tumor microenvironments

The FEBS Journal, Volume 293, Issue 1, Page 26-41, January 2026.
Intracellular communication controls the processing of generated signals so that every cell type can successfully respond. The extracellular matrix (ECM) is a fundamental regulator of cell communication and signaling through the strict orchestration and functions of its bioactive components.
Zoi Piperigkou, Sylvia Mangani, Nikolaos E. Koletsis, Christos Koutsakis, Nicholas S. Mastronikolis, Marco Franchi, Nikos K. Karamanos   +6 more
wiley   +1 more source

Kinesins in <i>Caenorhabditis elegans</i> neuronal morphogenesis. [PDF]

Open Biol
Niwa S, Chiba K.
europepmc   +1 more source

CDKL5 regulates the initiation of retrograde axonal transport through CLIP170–dynactin complex formation

The FEBS Journal, Volume 293, Issue 2, Page 456-474, January 2026.
Activation of CLIP170 by CDKL5 in wild‐type (WT) cells promotes its open conformation and association with tyrosinated microtubule (MT) plus‐ends (+), where it works as a docking site to recruit the dynactin–dynein–cargo complex, promoting the initiation of retrograde transport. In knock‐out (KO) neurons, CLIP170 is mainly present in a closed (inactive)
Serena Baldin, Clara Carmone, Giorgia Valetti, Roberta De Rosa, Isabella Barbiero   +4 more
wiley   +1 more source

A Case Report and Literature Review of Charcot-Marie-Tooth Disease Type 2F in a Family. [PDF]

Degener Neurol Neuromuscul Dis
Lei Y, Cheng L, Zhao W, Che P, Dong X, Ma L.   +5 more
europepmc   +1 more source