Results 191 to 200 of about 25,196 (259)

Exploring neuronal mechanisms of osteosarcopenia in older adults

open access: yesThe Journal of Physiology, Volume 604, Issue 2, Page 672-688, 15 January 2026.
Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley   +1 more source

Cell Motility Dynamics in Glaucoma: Mechanisms, Pathogenic Roles, and Therapeutic Targeting. [PDF]

open access: yesMedicina (Kaunas)
Rusciano D   +3 more
europepmc   +1 more source

Volitional exercise elicits physiological and molecular improvements in the severe D2.mdx mouse model of Duchenne muscular dystrophy

open access: yesThe Journal of Physiology, Volume 604, Issue 2, Page 849-867, 15 January 2026.
Abstract figure legend This study investigated the effects of volitional exercise on muscle health in the more severe D2.mdx model of Duchenne muscular dystrophy (DMD). We showed that 8–10 weeks of a relatively high volume of voluntary wheel running (VWR) in D2.mdx animals augmented select muscle mass and normalized ex vivo muscle force compared to ...
Stephanie R. Mattina   +7 more
wiley   +1 more source

Yifei Decoction Regulates the NGF/TRKA/PI3K/AKT Signaling Axis to Inhibit the Epithelial–Mesenchymal Transformation and Proliferation of Pulmonary Epithelial Cells in Bleomycin‐Induced Pulmonary Fibrogenesis

open access: yesCanadian Respiratory Journal, Volume 2026, Issue 1, 2026.
Background It was important to find better therapeutic drugs for idiopathic pulmonary fibrosis (IPF), and in our previous study, Yifei decoction (YFT) alleviated IPF. A deeper understanding of its mechanisms of action could aid in the development of novel treatment strategies.
Lijuan Chen   +9 more
wiley   +1 more source

Identification of miRNAs Expression Characteristics and Biomarkers in Serum‐Derived Exosomes of Wilson’s Disease Patients

open access: yesMediators of Inflammation, Volume 2026, Issue 1, 2026.
Background Wilson’s disease (WD), caused by mutations in the ATP7B gene, leads to copper accumulation and multi‐organ damage. Exosomal microRNAs (miRNAs) play a crucial role in cell‐to‐cell communication and the pathogenesis of diseases, yet their study in WD remains unreported.
Hong Chen   +6 more
wiley   +1 more source

Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization. [PDF]

open access: yesSci Adv
Carpentier R   +17 more
europepmc   +1 more source

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