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Clinical Neuropathology, 2020
Kinesins are microtubule-associated motor proteins involved in in regulating microtubule dynamics in neuronal and non-neuronal cells. However, the axonal cytoskeleton-related pathological changes in peripheral nerve have never been described in patients ...
K. Du +5 more
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Kinesins are microtubule-associated motor proteins involved in in regulating microtubule dynamics in neuronal and non-neuronal cells. However, the axonal cytoskeleton-related pathological changes in peripheral nerve have never been described in patients ...
K. Du +5 more
semanticscholar +1 more source
Axonal transport and the cytoskeleton
Current Opinion in Neurobiology, 1993Great advances in the field of axonal transport have been made in the past year, including the identification of new molecular motors associated with microtubules and actin. In addition, studies on the mechanisms of bidirectional fast axonal transport have clarified new aspects of this process, such as the isolation of a kinesin-binding protein ...
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The axonal cytoskeleton: stationary or moving matrix?
Trends in Neurosciences, 1988J. Bamburg
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A connected cytoskeleton network generates axonal tension in embryonic Drosophila.
Lab on a Chip, 2019Axons of neurons are contractile, i.e., they actively maintain a rest tension. However, the spatial origin of this contractility along the axon and the role of the cytoskeleton in generating tension and sustaining rigidity are unknown.
Anthony Fan, M. S. H. Joy, T. Saif
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Axonal pathology in Krabbe's disease: The cytoskeleton as an emerging therapeutic target
Journal of Neuroscience Research, 2016In Krabbe's disease (KD), demyelination and myelin‐independent axonal and neuronal defects contribute to the severe neuropathology. The toxic substrate that accumulates in this disease, psychosine, induces alterations in membrane lipid rafts with ...
Joana Nogueira-Rodrigues +2 more
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Slow transport of the cytoskeleton after axonal injury
Journal of Neurobiology, 1992AbstractThe delivery of cytoskeletal proteins to the axon occurs by slow axonal transport. We examined how the rate of slow transport was altered after axonal injury. When retinal ganglion cell (RGC) axons regenerated through peripheral nerve grafts, an increase in the rate of slow transport occurred during regrowth of the injured axons.
Andrea Hirscheimer, Lisa McKerracher
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The cytoskeleton as a modulator of tension driven axon elongation
Developmental Neurobiology, 2020AbstractThroughout development, neurons are capable of integrating external and internal signals leading to the morphological changes required for neuronal polarization and axon growth. The first phase of axon elongation occurs during neuronal polarization.
Mónica Mendes Sousa +2 more
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The cytoskeleton : a role in axonal transport and the synapse
2021This thesis was scanned from the print manuscript for digital preservation and is copyright the author. Researchers can access this thesis by asking their local university, institution or public library to make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
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Cytoskeleton, Axonal Transport, and the Mechanisms of Axonal Neuropathy
2010Axonal neuropathy, or axonopathy, is a major category of neuropathy in the central and peripheral nervous systems. Axonopathy is characterized by axonal degeneration and dysfunctional axonal transport. Peripheral axonopathies are more common than central axonopathies due to their lack of protection from the blood–brain barrier and resultant ...
Jacqueline R. Dauch +3 more
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The Cytoskeleton of the Squid Giant Axon
1990The squid giant axon is useful to biologists because of its very large size, but it is the continued applicability of studies on this cell to much smaller diameter mammalian axons that have sustained our interest in this mollusc. For example, in electrophysiology the large size of the squid giant axon has enabled manipulations that would have been ...
Anthony Brown, Raymond J. Lasek
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