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Axon cytoskeleton ultrastructure in chronic inflammatory demyelinating polyneuropathy
Muscle & Nerve, 2011AbstractIntroduction: To detail the extent and pattern of axon cytoskeleton alterations in chronic inflammatory demyelinating polyneuropathy (CIDP).Methods: Nerve biopsies from 7 cases of CIDP, including 4 cases with severe fiber loss, were compared with 5 controls by morphometric transmission electron microscopy (TEM).Results: Despite demyelination of
Fressinaud, Catherine, Dubas, Frédéric
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Translocation of the neuronal cytoskeleton and axonal locomotion
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1982Recent studies of axonal transport indicate that cytoskeletal proteins are assembled into polymers in the neuron cell body and that these polymers move from the cell body toward the end of the axon. On the other hand, membranous elements appear to be inserted into the axonal plasma membrane preferentially at the end of the axon.
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Maturation and aging of the axonal cytoskeleton: Biochemical analysis of transported tubulin
Journal of Neuroscience Research, 1991Changes in solubility and axonal transport of tubulin during maturation and aging have been investigated using sciatic motor fibers of rats at 4, 7, 14, 30, and 80 weeks of age.
T. Tashiro, Y. Komiya
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Calcium‐Mediated Degeneration of the Axonal Cytoskeleton in the Ola Mouse
Journal of Neurochemistry, 1994: The C57BL/Ola (Ola) mouse is a mutant substrain in which transected axons undergo very slow Wallerian degeneration. Because axonal degradation during Wallerian degeneration is calcium dependent, we tested whether Ola axons are susceptible to calcium ...
J. Glass, Brenda L. Schryer, J. Griffin
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Crosstalks Between Myelinating Cells and the Axonal Cytoskeleton
2010A constant and dynamic communication between axons and myelinating cells is necessary for the correct development, function, and maintenance of myelinated fibers. Recently, several studies highlighted the pivotal role of the axonal cytoskeleton in this reciprocal communication.
Perrot, Rodolphe, Eyer, Joël
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Annals of the New York Academy of Sciences, 1999
: Preferential distal axonal loss is a common feature of Charcot‐Marie‐Tooth (CMT) hereditary neuropathies. The general hypothesis tested here is that the axonal loss in these disorders is due to perturbed Schwann cell‐axon interactions resulting from ...
Z. Sahenk
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: Preferential distal axonal loss is a common feature of Charcot‐Marie‐Tooth (CMT) hereditary neuropathies. The general hypothesis tested here is that the axonal loss in these disorders is due to perturbed Schwann cell‐axon interactions resulting from ...
Z. Sahenk
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Effects of thiocolchicine on axonal cytoskeleton of the rat peroneus nerve
Experimental and Toxicologic Pathology, 2002Thiocolchicine is a colchicine-derivative used in the therapy of some diseases and extensively studied in the field of oncological research as antimitotic agent. Here we studied the activity of thiocolchicine on the cytoskeleton of the peroneus nerve, performing a histological and ultrastructural analysis.
FERRI, PAOLA +10 more
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Development of the Axonal and Dendritic Cytoskeleton
1995Publisher Summary This chapter discusses typical features of the axonal or dendritic cytoskeleton, their molecular and functional differences, and their potential role during dendritic or axonal development. Several mechanisms may be involved in the establishment of neuronal polarity, especially post-translational modifications that could influence ...
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Membrane and Cytoskeleton Dynamics During Axonal Elongation and Stabilization
2003Proper nervous activities are gradually developing events. Reflecting this, embryonic neurons start differentiation by sprouting multiple extensions, neurites, which do not bear clear axonal or dendritic structural and molecular characteristics.
Maria Dolores Ledesma, Carlos G. Dotti
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