Results 231 to 240 of about 25,196 (259)
Some of the next articles are maybe not open access.
Post-Acute Alterations in the Axonal Cytoskeleton after Traumatic Axonal Injury
Journal of Neurotrauma, 2003All previous analyses of axonal responses to traumatic axonal injury (TAI) have described the ultrastructure of changes in the cytoskeleton and axolemma within 6 h of injury. In the present study we tested the hypothesis that there are, in addition, ultrastructural pathological changes up to 1 week after injury.
William L, Maxwell +4 more
openaire +2 more sources
Axonal transport and the cytoskeleton
Current Opinion in Neurobiology, 1993Great advances in the field of axonal transport have been made in the past year, including the identification of new molecular motors associated with microtubules and actin. In addition, studies on the mechanisms of bidirectional fast axonal transport have clarified new aspects of this process, such as the isolation of a kinesin-binding protein ...
openaire +2 more sources
Neurotoxic probes of the axonal cytoskeleton
Trends in Neurosciences, 1983Abstract Neurofibrillary changes, characterized by accumulations of neurofilaments within the neuronal perikaryon or axon, occur in a variety of human and experimental disorders. The pathogenesis of one model, β,β′-iminodipropionitrile (IDPN) toxicity, is partially understood. IDPN produces a distinctive alteration in which microtubules are segregated
John W. Griffin +2 more
openaire +1 more source
Slow transport of the cytoskeleton after axonal injury
Journal of Neurobiology, 1992AbstractThe delivery of cytoskeletal proteins to the axon occurs by slow axonal transport. We examined how the rate of slow transport was altered after axonal injury. When retinal ganglion cell (RGC) axons regenerated through peripheral nerve grafts, an increase in the rate of slow transport occurred during regrowth of the injured axons.
L, McKerracher, A, Hirscheimer
openaire +2 more sources
Axon cytoskeleton ultrastructure in chronic inflammatory demyelinating polyneuropathy
Muscle & Nerve, 2011AbstractIntroduction: To detail the extent and pattern of axon cytoskeleton alterations in chronic inflammatory demyelinating polyneuropathy (CIDP).Methods: Nerve biopsies from 7 cases of CIDP, including 4 cases with severe fiber loss, were compared with 5 controls by morphometric transmission electron microscopy (TEM).Results: Despite demyelination of
Fressinaud, Catherine, Dubas, Frédéric
openaire +3 more sources
Axonal degeneration and disorders of the axonal cytoskeleton
1995Abstract This chapter discusses cytoskeletal changes in axonal degeneration. It begins with a review of the organization of the normal axonal cytoskeleton, followed by a summary of the current understanding of Wallerian degeneration. It then considers the slowly evolving axonal degenerations in which alterations in neurofilament content ...
JOHN W. GRIFFIN +3 more
openaire +1 more source
Cytoskeleton, Axonal Transport, and the Mechanisms of Axonal Neuropathy
2010Axonal neuropathy, or axonopathy, is a major category of neuropathy in the central and peripheral nervous systems. Axonopathy is characterized by axonal degeneration and dysfunctional axonal transport. Peripheral axonopathies are more common than central axonopathies due to their lack of protection from the blood–brain barrier and resultant ...
Hsinlin T. Cheng +3 more
openaire +1 more source
Translocation of the neuronal cytoskeleton and axonal locomotion
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1982Recent studies of axonal transport indicate that cytoskeletal proteins are assembled into polymers in the neuron cell body and that these polymers move from the cell body toward the end of the axon. On the other hand, membranous elements appear to be inserted into the axonal plasma membrane preferentially at the end of the axon.
openaire +2 more sources
The Role of the Axonal Cytoskeleton in Diabetic Neuropathy
Neurochemical Research, 1997The neuropathy associated with diabetes includes well documented impairment of axonal transport, a reduction in axon calibre and a reduced capacity for nerve regeneration. All of those aspects of nerve function rely on the integrity of the axonal cytoskeleton.
openaire +2 more sources
The Cytoskeleton of the Squid Giant Axon
1990The squid giant axon is useful to biologists because of its very large size, but it is the continued applicability of studies on this cell to much smaller diameter mammalian axons that have sustained our interest in this mollusc. For example, in electrophysiology the large size of the squid giant axon has enabled manipulations that would have been ...
Anthony Brown, Raymond J. Lasek
openaire +1 more source